Evidence map›Paper›PMID 23768903›Full record

ArticleBiomaterials2013

Imaging challenges in biomaterials and tissue engineering.

Alyssa A Appel, Mark A Anastasio, Jeffery C Larson, Eric M Brey

Abstract read
In one paragraph

Article in Biomaterials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Digital Light Processing ofMaterials (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Multiscale confocal photoacoustic dermoscopy to evaluate skin health.Quantitative imaging in medicine and surgery · 2022
    Article
  15. Article
  16. Article
  17. Recent advances in regenerative biomaterials.Regenerative biomaterials · 2022
    Review
  18. Review
  19. Article
  20. Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alyssa A AppelDepartment of Biomedical Engineering, Illinois Institute of Technology, 3255 South Dearborn St, Chicago, IL 60616, USA.
Mark A Anastasio
Jeffery C Larson
Eric M Brey

Funding

Design Studies and Optimization of Phase-Contrast MammographyR01EB009715 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2010 to 2013
$1.6M
Synthetic Matrices for Vascularization of Engineered TissuesI01BX000418 · VA · EDWARD HINES JR VA HOSPITAL · PI BREY, ERIC M · 2010 to 2017
–
BLRD VA I01 BX000418NIBIB NIH HHS R01 EB009715NIBIB NIH HHS R01EB009715
6 · The paper itself

Abstract

Biomaterials are employed in the fields of tissue engineering and regenerative medicine (TERM) in order to enhance the regeneration or replacement of tissue function and/or structure. The unique environments resulting from the presence of biomaterials, cells, and tissues result in distinct challenges in regards to monitoring and assessing the results of these interventions. Imaging technologies for three-dimensional (3D) analysis have been identified as a strategic priority in TERM research. Traditionally, histological and immunohistochemical techniques have been used to evaluate engineered tissues. However, these methods do not allow for an accurate volume assessment, are invasive, and do not provide information on functional status. Imaging techniques are needed that enable non-destructive, longitudinal, quantitative, and three-dimensional analysis of TERM strategies. This review focuses on evaluating the application of available imaging modalities for assessment of biomaterials and tissue in TERM applications. Included is a discussion of limitations of these techniques and identification of areas for further development.

Indexed as

Magnetic Resonance ImagingMolecular ImagingBiocompatible MaterialsHumansRegenerative MedicineTissue EngineeringBiocompatible Materials

Identifiers

PMID23768903
PMCPMC3799904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.