Evidence map›Paper›PMID 23768489›Full record

ReviewCell host & microbe2013

The normalcy of dormancy: common themes in microbial quiescence.

Emily S C Rittershaus, Seung-Hun Baek, Christopher M Sassetti

Abstract readReview
In one paragraph

Review in Cell host & microbe, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 185 papers.

0numbers the graph read from it
0cells of the map it votes in
185citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

185 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Quiescence improvesbioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Article
  12. Sepsis as CNS-governed metabolic triage.Frontiers in immunology · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. Boundary conditions for exploiting the cooperation ofApplied and environmental microbiology · 2025
    Article
  17. Article
  18. Article
  19. Overcoming toxicity: How nonantagonistic microbes manage to thrive in boom-and-bust environments.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

125 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily S C RittershausDepartment of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Seung-Hun Baek
Christopher M Sassetti

Funding

Tuberculosis Pathogenesis and Drug ResponseR01AI064282 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SASSETTI, CHRISTOPHER M · 2007 to 2017
$3.9M
Howard Hughes Medical InstituteNIAID NIH HHS AI064282NIAID NIH HHS R01 AI064282
6 · The paper itself

Abstract

All microorganisms are exposed to periodic stresses that inhibit growth. Many bacteria and fungi weather these periods by entering a hardy, nonreplicating state, often termed quiescence or dormancy. When this occurs during an infection, the resulting slowly growing pathogen is able to tolerate both immune insults and prolonged antibiotic exposure. While the stresses encountered in a free-living environment may differ from those imposed by host immunity, these growth-limiting conditions impose common pressures, and many of the corresponding microbial responses appear to be universal. In this review, we discuss the common features of these growth-limited states, which suggest new approaches for treating chronic infections such as tuberculosis.

Indexed as

Stress, PhysiologicalBacteriaDrug Resistance, MicrobialFungi

Identifiers

PMID23768489
PMCPMC3743100

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.