ReviewAnnual review of microbiology2013
Bacterial responses to reactive chlorine species.
Review in Annual review of microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 1 synthesis or guideline pooled it, 297 citations in OpenAlex.
- Effect of a sodium hypochlorite mouthwash on plaque and clinical parameters of periodontal disease-a systematic review.International journal of dental hygiene · 2022Pooled it
- Redox protection by bacterial glutathione peroxidase drives virulence inRedox report : communications in free radical research · 2026Article
- Electrolyzed Water as a Biocide in Premise Water Networks: A Narrative Review and a Conceptual Framework.Pathogens (Basel, Switzerland) · 2026Review
- Implications of bacterial exposure to reactive oxygen and chlorine species.Infection and immunity · 2026Review
- Toward Robust ARB Inactivation in Wastewater: Comparing Performic Acid, Peracetic Acid, and Chloramination Using ICT, Resistance, and Reactivation Metrics.Water environment research : a research publication of the Water Environment Federation · 2026Article
- Disinfection performance of mixed oxidant, NaClO, and Ca(ClO)Environmental science and pollution research international · 2026Article
- Managing dangerous liaisons: lessons fromJournal of bacteriology · 2026Review
- Complexity of Chloramine Decay Kinetics in Premise Plumbing.ACS ES&T water · 2026Article
- New insights into the stress response mechanisms of stress-resistantEmerging microbes & infections · 2025Article
- Red Emissive Carbon Dots as Fluorescent Probe for Specific Sensing and Imaging of HCIO.Journal of fluorescence · 2025Article
- Studies of the membrane-bound flavocytochrome MsrQ flavin mononucleotide (FMN)-binding site reveal an unexpected ubiquinone cofactor.The FEBS journal · 2025Article
- Repair of oxidized methionine residues in the chaperone Spy maintains periplasmic proteostasis under chlorite stress in Escherichia coli.PLoS biology · 2025Article
- Article
- Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow.bioRxiv : the preprint server for biology · 2025Article
- Genome-wide characterization of hypothiocyanite stress response inJournal of bacteriology · 2025Article
- Photobleaching of Light-Activated Porphyrin-Functionalized Plastic Coupons for Potential Antimicrobial Applications.ACS materials Au · 2025Article
- A Novel Silver-Ruthenium-Based Antimicrobial Kills Gram-Negative Bacteria Through Oxidative Stress-Induced Macromolecular Damage.bioRxiv : the preprint server for biology · 2025Article
- Varying effects of chlorination on microbial functional repertoire and gene expression in contrasting effluents.Frontiers in microbiology · 2025Article
- Formylation facilitates the reduction of oxidized initiator methionines.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The role of exopolysaccharides Psl and Pel in resistance ofMicrobiology spectrum · 2024Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Hypochlorous acid (HOCl), the active ingredient of household bleach, is the most common disinfectant in medical, industrial, and domestic use and plays an important role in microbial killing in the innate immune system. Given the critical importance of the antimicrobial properties of chlorine to public health, it is surprising how little is known about the ways in which bacteria sense and respond to reactive chlorine species (RCS). Although the literature on bacterial responses to reactive oxygen species (ROS) is enormous, work addressing bacterial responses to RCS has begun only recently. Transcriptomic and proteomic studies now provide new insights into how bacteria mount defenses against this important class of antimicrobial compounds. In this review, we summarize the current knowledge, emphasizing the overlaps between RCS stress responses and other more well-characterized bacterial defense systems, and identify outstanding questions that represent productive avenues for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.