ReviewTheScientificWorldJournal2013
Will the SAFE strategy be sufficient to eliminate trachoma by 2020? Puzzlements and possible solutions.
Review in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Trachoma.BMJ clinical evidence · 2016Pooled it
- Effect of water, sanitation, and hygiene on the prevention of trachoma: a systematic review and meta-analysis.PLoS medicine · 2014Pooled it
- The prevention and management of postoperative trachomatous trichiasis: A systematic review.Survey of ophthalmologyPooled it
- Assessing trachoma elimination progress in districts with persistent trachoma, Western Province, Zambia.International health · 2025Article
- Analysis and forecast of the disease burden of trachoma in China and the Global Population over 15 years of age, 1990-2021.PLoS neglected tropical diseases · 2025Article
- District-Level Forecast of Achieving Trachoma Elimination as a Public Health Problem By 2030: An Ensemble Modelling Approach.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Knowledge, Practice and Associated Factor of Trachoma Transmission and Prevention Among Primary School Students in Addis Zemen Town, South Gondar, Northwest Ethiopia.Environmental health insights · 2024Article
- Trachoma prevention practice and associated factors among mothers having children aged under nine years in Andabet district, northwest Ethiopia, 2022: A multi-level analysis.PLoS neglected tropical diseases · 2023Article
- Assessment of the status of improved F&E trachoma control practices among children of agro-pastoralists in Southern Ethiopia: a mixed design survey using theory of triadic influences.BMC public health · 2023Article
- Trachoma Prevention Practice and Associated Factors in Rural Lemo District, Southern Ethiopia, 2021.Ethiopian journal of health sciences · 2023Article
- Model-based geostatistics enables more precise estimates of neglected tropical-disease prevalence in elimination settings: mapping trachoma prevalence in Ethiopia.International journal of epidemiology · 2022Article
- Exploring barriers for trachomatous trichiasis surgery implementation in gamo zone, Southern Ethiopia.PLoS neglected tropical diseases · 2021Article
- Knowledge, Attitude, Practices and Associated Factors Towards Trachoma Among People Living in Arba Minch Zuria District, Gamo Zone, Southern Ethiopia.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Review
- Prevalence of Active Trachoma and Associated Factors in Areka Town, South Ethiopia, 2018.Interdisciplinary perspectives on infectious diseases · 2020Article
- Trachomatous scarring among children in a formerly hyper-endemic district of Tanzania.PLoS neglected tropical diseases · 2017Article
- Survey, Culture, and Genome Analysis of OcularFrontiers in cellular and infection microbiology · 2016Article
- Social Sciences for the Prevention of Blindness.Tropical medicine and health · 2015Review
- Short term outcome of anterior lamellar reposition in treating trachomatous trichiasis.Journal of ophthalmology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the inception of (the Global Elimination of Blinding Trachoma) GET 2020 in 1997 and the implementation of the SAFE strategy a year later, much progress has been made toward lowering the prevalence of trachoma worldwide with elimination of the disease in some countries. However, high recurrence of trichiasis after surgery, difficulty in controlling the reemergence of infection after mass distribution of azithromycin in some communities, the incomplete understanding of environment in relation to the disease, and the difficulty in establishing the prevalence of the disease in low endemic areas are some of the issues still facing completion of the GET 2020 goals. In this narrative review, literature was searched from 1998 to January 2013 in PubMed for original studies and reviews. Reasons for these ongoing problems are discussed, and several suggestions are made as avenues for exploration in relation to improving the SAFE strategy with emphasis on improving surgical quality and management of the mass treatment with antibiotics. In addition, more research needs to be done to better understand the approach to improve sanitation, hygiene, and environment. The main conclusion of this review is that scale-up is needed for all SAFE components, and more research should be generated from communities outside of Africa and Asia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.