ArticleInternational journal of nanomedicine2013
Engineering of epidermis skin grafts using electrospun nanofibrous gelatin/ polycaprolactone membranes.
Article in International journal of nanomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Development and Evaluation of Biodegradable Core-Shell Microfibrous and Nanofibrous Scaffolds for Tissue Engineering Applications.Journal of materials science. Materials in medicine · 2024Article
- Osteoinductive Electrospun Scaffold Based on PCL-Col as a Regenerative Therapy for Peri-Implantitis.Pharmaceutics · 2023Article
- Review
- Electrospun nano-fibrous bilayer scaffold prepared from polycaprolactone/gelatin and bioactive glass for bone tissue engineering.Journal of materials science. Materials in medicine · 2021Article
- Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration.Pharmaceutics · 2020Review
- Bovine Decellularized Amniotic Membrane: Extracellular Matrix as Scaffold for Mammalian Skin.Polymers · 2020Article
- Fabrication of Nanofibrous/Xerogel Layer-by-Layer Biocomposite Scaffolds for Skin Tissue Regeneration: In Vitro Study.ACS omega · 2020Article
- Development of nanotechnology for advancement and application in wound healing: a review.IET nanobiotechnology · 2019Review
- Electrospun gelatin/PCL and collagen/PCL scaffolds for modulating responses of bone marrow endothelial progenitor cells.Experimental and therapeutic medicine · 2019Article
- Article
- Biosynthetic PCL-graft-Collagen Bulk Material for Tissue Engineering Applications.Materials (Basel, Switzerland) · 2017Article
- Recent advances in electrospun nanofibers for wound healing.Nanomedicine (London, England) · 2017Review
- Electrospun Polycaprolactone/Aloe Vera_Chitosan Nanofibrous Asymmetric Membranes Aimed for Wound Healing Applications.Polymers · 2017Article
- Bioresorbable scaffold as a dermal substitute.International journal of burns and trauma · 2017Article
- Characterization of A Three-Dimensional Organotypic Co-Culture Skin Model for Epidermal Differentiation of Rat Adipose-Derived Stem Cells.Cell journal · 2016Article
- Microporous dermal-mimetic electrospun scaffolds pre-seeded with fibroblasts promote tissue regeneration in full-thickness skin wounds.PloS one · 2015Article
- Advancement of wound care from grafts to bioengineered smart skin substitutes.Progress in biomaterials · 2014Review
- Tunable engineered skin mechanics via coaxial electrospun fiber core diameter.Tissue engineering. Part A · 2014Article
- Enrichment of breast cancer stem-like cells by growth on electrospun polycaprolactone-chitosan nanofiber scaffolds.International journal of nanomedicine · 2014Article
- Electrospun gelatin/PCL and collagen/PLCL scaffolds for vascular tissue engineering.International journal of nanomedicine · 2014Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skin engineering provides a new strategy for treating a wide variety of skin defects. In particular, electrospun nanofibrous membranes have been used as carriers for epidermis engineering. The aim of this study was to investigate the feasibility of a modified gelatin and polycaprolactone (GT/PCL) electrospun membrane for epidermis engineering. The biocompatibility of the membranes was evaluated by seeding HaCaT cells (human keratinocyte cell line) on the membrane and the mechanical properties of the membranes were determined with and without cells after culture. A cell proliferation assay showing that HaCaT cells attached and proliferated well on the membranes demonstrated that the membranes possess good biocompatibility. Mechanical tests showed that the membranes are strong enough to be handled during transplantation. Further in vivo transplantation studies revealed that epidermises engineered with GT/PCL membranes were able to repair skin defects in the nude mouse. These results demonstrate that GT/PCL electrospun membranes could be suitable scaffolds for skin engineering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.