Trial reportSurgical endoscopy2013
Tunneling endoscopic muscularis dissection for subepithelial tumors originating from the muscularis propria of the esophagus and gastric cardia.
Trial report in Surgical endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Submucosal Tunneling Endoscopic Resection for Upper Gastrointestinal Subepithelial Lesions: A Systematic Review and Meta-Analysis.Journal of gastrointestinal cancer · 2025Pooled it
- Clinicopathological features of esophageal schwannomas in mainland China: systematic review of the literature.International journal of clinical oncology · 2021Pooled it
- Efficacy and safety of submucosal tunneling endoscopic resection for upper gastrointestinal submucosal tumors: a systematic review and meta-analysis.Surgical endoscopy · 2017Pooled it
- Esophageal endoscopic muscularis dissection with a tunnel-first approach for deeply invasive Barrett's adenocarcinoma.Endoscopy · 2026Article
- [Management of Colorectal Subepithelial Lesions: Differential Diagnosis and Follow-up].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- The efficacy of full-thickness endoscopic resection of subepithelial tumors in the gastric cardia.World journal of gastrointestinal oncology · 2023Article
- Total removal of a large esophageal schwannoma by submucosal tunneling endoscopic resection: A case report and review of literature.World journal of clinical cases · 2023Article
- Landscape of esophageal submucosal tunneling endoscopic resection-related adverse events in a standardized lexicon: a large volume of 1701 cases.Surgical endoscopy · 2022Article
- Risk stratification in patients with upper gastrointestinal submucosal tumors undergoing submucosal tunnel endoscopic resection.Frontiers in medicine · 2022Article
- Submucosal tunneling endoscopic resection of an exogenic esophageal mass in the mediastinum (with video).Gastroenterology report · 2021Article
- Endoscopic resection of benign esophageal schwannoma: Three case reports and review of literature.World journal of clinical cases · 2020Article
- Clinical Efficacy of Single-Channel Gastroscopy, Double-Channel Gastroscopy, and Double Gastroscopy for Submucosal Tumors in the Cardia and Gastric Fundus.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Mucosal loss as a critical factor in esophageal stricture formation after mucosal resection: a pilot experiment in a porcine model.Surgical endoscopy · 2020Article
- Endoscopic Esophageal Submucosal Tunnel Dissection for Cystic Lesions Originating from the Muscularis Propria of the Gastric Cardia.Journal of oncology · 2020Article
- Comparison of different endoscopic resection techniques for submucosal tumors originating from muscularis propria at the esophagogastric junction.BMC gastroenterology · 2019Article
- Comparison Between Submucosal Tunneling Endoscopic Resection (STER) and Other Resection Modules for Esophageal Muscularis Propria Tumors: A Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Consensus on the digestive endoscopic tunnel technique.World journal of gastroenterology · 2019Article
- Submucosal tunneling endoscopic resection: An effective and safe therapy for upper gastrointestinal submucosal tumors originating from the muscularis propria layer.World journal of gastroenterology · 2019Article
- Endoscopic resection for subepithelial lesions-pure endoscopic full-thickness resection and submucosal tunneling endoscopic resection.Translational gastroenterology and hepatology · 2019Review
- Endoscopic full thickness resection versus submucosal tunneling endoscopic resection for removal of submucosal tumors: a review article.Translational gastroenterology and hepatology · 2019Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsEndoscopic resection of esophageal or cardial subepithelial tumors (SETs) originating from the muscularis propria (MP) is rarely done due to the high risk of perforation, fistula formation, and secondary infection. The aim of this study was to evaluate the preliminary clinical feasibility and safety of tunneling endoscopic muscularis dissection (tEMD) for resection of SETs located in the esophagus and gastric cardia
methodsTwelve patients with SETs originating from the MP of the esophagus (n = 7) or cardia (n = 5) were treated by tEMD. The procedure included creation of a submucosal tunnel to reach the tumor, dissection of the tumor from the surrounding submucosal tissue and the unaffected MP layer, full-thickness resection of the tumor and affected MP, and subsequent closure of the tunnel mucosal entry with endoscopic clips.
resultsThe en bloc resection rate was 100 % (seven lesions affected the deep MP so complete MP resection was performed; five lesions affected the superficial MP for a partial MP resection). The average tumor size was 18.5 ± 6.9 (range 10-30) mm. The mean operating time was 78.3 ± 25.5 (range 50-130) min. The histological diagnoses were two gastrointestinal stromal tumors with very low risk, nine leiomyomas, and one schwannoma. Air leakage and effusion included subcutaneous and mediastinal emphysema in eight patients (66.7 %), pneumothorax in four (33.3 %), pneumoperitoneum in three (25.0 %), and small pleural effusion in two (16.7 %). All air leakage and effusion cases were resolved with conservative management. No patient developed delayed hemorrhage and chronic fistula after tEMD. During the mean follow-up time of 7.1 ± 4.3 (range 2-15) months, no tumor recurrence was found in any patient.
conclusionstEMD appears to be a feasible minimally invasive and effective treatment for patients with SETs originating from the MP layer of the esophagus and cardia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.