Evidence map›Paper›PMID 23765287›Full record

ArticleBiomolecular NMR assignments2014

¹H, ¹³C and ¹⁵N NMR assignments of a Drosophila Hedgehog autoprocessing domain.

Jian Xie, Zhenming Du, Brian Callahan, Marlene Belfort, Chunyu Wang

Open access · greenAbstract read
In one paragraph

Article in Biomolecular NMR assignments, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Active site targeting of hedgehog precursor protein with phenylarsine oxide.Chembiochem : a European journal of chemical biology · 2015
    Article
  7. Thiol-based redox switches.Biochimica et biophysica acta · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jian XieBiochemistry and Biophysics Graduate Program, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.
Zhenming Du
Brian Callahan
Marlene Belfort
Chunyu Wang
Rensselaer Polytechnic Institute · USBinghamton University · USUniversity at Albany, State University of New York · US

Funding

SELF-SPLICING INTEINS: FUNCTION, EVOLUTION, APPLICATIONR01GM044844 · NIGMS · WADSWORTH CENTER · PI BELFORT, MARLENE · 1990 to 2019
$8.9M
Testing novel hypotheses in Mtu RecA intein splicingR01GM081408 · NIGMS · RENSSELAER POLYTECHNIC INSTITUTE · PI WANG, CHUNYU · 2007 to 2011
$1.7M
NIGMS NIH HHS R01 GM044844NIGMS NIH HHS R01 GM081408NIGMS NIH HHS R01GM081408NIGMS NIH HHS R01GM44844
6 · The paper itself

Abstract

The Hedgehog (Hh) signaling pathway plays important roles in embryonic growth and patterning in different organisms. Abnormal activity of the Hh signaling pathway has been associated to cancers, holoprosencephaly and autism spectrum disorders. The backbone and side chain resonance assignments of a Drosophila Hh autoprocessing domain have been determined based on triple-resonance experiments with the [(13)C, (15)N]-labeled and [(2)H, (13)C, (15)N])-labeled proteins.

Indexed as

Drosophila melanogasterNuclear Magnetic Resonance, BiomolecularAnimalsDrosophila ProteinsHedgehog ProteinsProtein Structure, TertiaryDrosophila ProteinsHedgehog Proteins

Identifiers

PMID23765287
PMCPMC3884045
OpenAlexW2017161894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.