Evidence map›Paper›PMID 23765269›Full record

ArticleMolecular biology of the cell2013

Biology is more theoretical than physics.

Jeremy Gunawardena

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. From Gregor Mendel to Eric Davidson: Mathematical Models and Basic Principles in Biology.Journal of computational biology : a journal of computational molecular cell biology · 2019
    Article
  4. Article
  5. Article
  6. Article
  7. Nucleosomes, transcription, and probability.Molecular biology of the cell · 2014
    Article
  8. Article
  9. Article
  10. Review
  11. Cell responses only partially shape cell-to-cell variations in protein abundances in Escherichia coli chemotaxis.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jeremy GunawardenaDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. jeremy@hms.harvard.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The word "theory" is used in at least two senses--to denote a body of widely accepted laws or principles, as in "Darwinian theory" or "quantum theory," and to suggest a speculative hypothesis, often relying on mathematical analysis, that has not been experimentally confirmed. It is often said that there is no place for the second kind of theory in biology and that biology is not theoretical but based on interpretation of data. Here, ideas from a previous essay are expanded upon to suggest, to the contrary, that the second kind of theory has always played a critical role and that biology, therefore, is a good deal more theoretical than physics.

Indexed as

Models, BiologicalQuantum TheoryBiological PhenomenaBiologyBiophysical PhenomenaBiophysicsKineticsPhysical PhenomenaPhysics

Identifiers

PMID23765269
PMCPMC3681688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.