Evidence map›Paper›PMID 23765237›Full record

Observational studyIntensive care medicine2013

The ETHICA study (part II): simulation study of determinants and variability of ICU physician decisions in patients aged 80 or over.

M Garrouste-Orgeas, A Tabah, A Vesin, F Philippart, A Kpodji, C Bruel, C Grégoire, A Max, J F Timsit, B Misset

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02852629 (Assessment of a Tool for Decision Making in Case of Worsening Condition of Cancer Patients), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02852629 completednot on this mapstarted 2014, after this paper: background citation

Assessment of a Tool for Decision Making in Case of Worsening Condition of Cancer Patients

TypeobservationalSponsorUniversity Hospital, GrenobleRan2014 to 2016Enrolled483ConditionsLung CancerArmsobservational study
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ableism in the intensive care unit.Intensive care medicine · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Identifying ICU admission decision patterns in a '20-questions game' approach using network analysis.The Southern African journal of critical care : the official journal of the Critical Care Society · 2021
    Article
  16. Article
  17. Article
  18. Simulation Training in Hemodynamic Monitoring and Mechanical Ventilation: An Assessment of Physician's Performance.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

M Garrouste-OrgeasMedical-Surgical, Saint Joseph Hospital Network, 185 rue Raymond Losserand, 75014, Paris, France. mgarrouste@hpsj.fr
A Tabah
A Vesin
F Philippart
A Kpodji
C Bruel
C Grégoire
A Max
J F Timsit
B Misset

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess physician decisions about ICU admission for life-sustaining treatments (LSTs).

methodsObservational simulation study of physician decisions for patients aged ≥80 years. Each patient was allocated at random to four physicians who made decisions based on actual bed availability and existence of an additional bed before and after obtaining information on patient preferences. The simulations involved non-invasive ventilation (NIV), invasive mechanical ventilation (IMV), and renal replacement therapy after a period of IMV (RRT after IMV).

resultsThe physician participation rate was 100/217 (46 %); males without religious beliefs predominated, and median ICU experience was 9 years. Among participants, 85.7, 78, and 62 % felt that NIV, IMV, or RRT (after IMV) was warranted, respectively. By logistic regression analysis, factors associated with admission were age <85 years, self-sufficiency, and bed availability for NIV and IMV. Factors associated with IMV were previous ICU stay (OR 0.29, 95 % CI 0.13-0.65, p = 0.01) and cancer (OR 0.23, 95 % CI 0.10-0.52, p = 0.003), and factors associated with RRT (after IMV) were living spouse (OR 2.03, 95 % CI 1.04-3.97, p = 0.038) and respiratory disease (OR 0.42, 95 % CI 0.23-0.76, p = 0.004). Agreement among physicians was low for all LSTs. Knowledge of patient preferences changed physician decisions for 39.9, 56, and 57 % of patients who disagreed with the initial physician decisions for NIV, IMV, and RRT (after IMV) respectively. An additional bed increased admissions for NIV and IMV by 38.6 and 13.6 %, respectively.

conclusionsPhysician decisions for elderly patients had low agreement and varied greatly with bed availability and knowledge of patient preferences.

Indexed as

Attitude of Health PersonnelIntensive Care UnitsPractice Patterns, Physicians'Renal Replacement TherapyRespiration, ArtificialTriageAged, 80 and overDecision MakingFemaleHumansMale

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.