ArticleLeukemia2013
Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies.
Article in Leukemia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Article
- RIT1 Drives Oncogenic Transformation and Is an Actionable Target in Lung Adenocarcinoma.Cancer research · 2025Article
- Article
- RIT1 Promotes the Proliferation of Gliomas Through the Regulation of the PI3K/AKT/c-Myc Signalling Pathway.Journal of cellular and molecular medicine · 2025Article
- Article
- A microglia clonal inflammatory disorder in Alzheimer's Disease.bioRxiv : the preprint server for biology · 2024Article
- RIT1 regulates mitosis and promotes proliferation by interacting with SMC3 and PDS5 in hepatocellular carcinoma.Journal of experimental & clinical cancer research : CR · 2023Article
- RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophy.Science advances · 2023Article
- Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.Cancer discovery · 2022Article
- Noonan syndrome caused by RIT1 gene mutation: A case report and literature review.Frontiers in pediatrics · 2022Article
- Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.Science signaling · 2021Article
- Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer.Nature communications · 2021Article
- Genomic variations in patients with myelodysplastic syndrome and karyotypes without numerical or structural changes.Scientific reports · 2021Article
- Genome-wide CRISPR screening reveals novel therapeutic targets in RIT1-driven lung cancer.Molecular & cellular oncology · 2021Article
- The molecular functions of RIT1 and its contribution to human disease.The Biochemical journal · 2020Review
- Genetic basis of myelodysplastic syndromes.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2020Review
- New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis.EBioMedicine · 2019Article
- RIT1 oncoproteins escape LZTR1-mediated proteolysis.Science (New York, N.Y.) · 2019Article
- RIT1 suppresses esophageal squamous cell carcinoma growth and metastasis and predicts good prognosis.Cell death & disease · 2018Article
- Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.Nature communications · 2018Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.