Evidence map›Paper›PMID 23764885›Full record

SynthesisNeurorehabilitation and neural repair2013

Rehabilitating walking speed poststroke with treadmill-based interventions: a systematic review of randomized controlled trials.

Charalambos C Charalambous, Heather Shaw Bonilha, Steven A Kautz, Chris M Gregory, Mark G Bowden

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Neurorehabilitation and neural repair, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Treadmill training and body weight support for walking after stroke.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Treadmill training and body weight support for walking after stroke.The Cochrane database of systematic reviews · 2014
    Pooled it
  4. Exploiting telerobotics for sensorimotor rehabilitation: a locomotor embodiment.Journal of neuroengineering and rehabilitation · 2021
    Trial
  5. Trial
  6. Trial
  7. Effects of unilateral real-time biofeedback on propulsive forces during gait.Journal of neuroengineering and rehabilitation · 2017
    Trial
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Charalambos C Charalambous1Medical University of South Carolina, Charleston, SC, USA.
Heather Shaw Bonilha
Steven A Kautz
Chris M Gregory
Mark G Bowden
Medical University of South Carolina · USRalph H. Johnson VA Medical Center · US

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
South Carolina Clinical & Translational Research Institute (SCTR)KL2RR029880 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2009 to 2011
$1.2M
South Carolina Clinical & Translational Research Institute (SCTR)KL2TR000060 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$807k
Augmentation of Locomotor Adaptation Post-StrokeIK2RX000787 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI BOWDEN, MARK G. · 2015 to 2017
–
NCATS NIH HHS KL2 TR000060NCRR NIH HHS KL2 RR029880NIGMS NIH HHS P20 GM109040RRD VA IK2 RX000787
6 · The paper itself

Abstract

backgroundIn the past several years, several randomized controlled trials (RCTs) have been reported regarding the efficacy of treadmill-based walking-specific rehabilitation programs, either individually (TT) or combined with body weight support (BWSTT), over control group therapies poststroke. No clear consensus exists as to whether treadmill-based interventions are superior in rehabilitating walking speed (WS) poststroke.

objectiveTo review published RCTs examining TT and BWSTT poststroke and describe the effects on improving and retaining WS.

methodsA systematic literature search in computerized databases was conducted to identify RCTs whose methodological quality was assessed with PEDro. Pre- and post-WS, change in WS, functional outcomes, and follow-up speed were extracted and calculated from each study. Additionally, statistical results of each study were examined, and the intragroup and intergroup effect sizes (ESintra and ESinter, respectively) were calculated.

resultsAll studies (8 TT; 7 BWSTT) met the inclusion criteria, and their methodological quality was generally good, with a mean PEDro score 6.9/10. Of the 15 studies, 8 studies (4 TT; 4 BWSTT) reported intragroup significant increases of WS, whereas only 4 (4 TT) found superiority of treadmill interventions. Nine studies demonstrated large ESintra (4 TT; 5 BWSTT), yet only 3 showed large ESinter (1 TT; 2 BWSTT). Four studies (2 TT and 2 BWSTT) reported retention of gains in WS, regardless of intervention.

conclusionsTreadmill-based interventions poststroke may increase and retain WS, but their universal superiority to other control group therapies has failed to be established.

Indexed as

Exercise TestStroke RehabilitationWalkingAgedFemaleHumansMaleMiddle AgedRandomized Controlled Trials as Topicactivity-based interventionscerebrovascular accidentrehabilitationwalking

Identifiers

PMID23764885
PMCPMC4478607
OpenAlexW2087173370

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.