Evidence map›Paper›PMID 23764638›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2013

Integrated strategies for combination HIV prevention: principles and examples for men who have sex with men in the Americas and heterosexual African populations.

Connie Celum, Jared M Baeten, James P Hughes, Ruanne Barnabas, Albert Liu, Heidi Van Rooyen, Susan Buchbinder

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. HIV Prevention Interventions for Adolescents.Current HIV/AIDS reports · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. PrEP Implementation Science: State-of-the-Art and Research Agenda.Journal of the International AIDS Society · 2015
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Connie CelumDepartment of Global Health and Medicine, University of Washington, Seattle, WA 98104, USA. ccelum@uw.edu
Jared M Baeten
James P Hughes
Ruanne Barnabas
Albert Liu
Heidi Van Rooyen
Susan Buchbinder

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI MYRON Scott COHEN, Sinead Delany-Moretlwe · 2011 to 2026
$779.5M
San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
Interventions to decrease HIV infectiousness in UgandaRC4AI092552 · NIAID · UNIVERSITY OF WASHINGTON · PI CELUM, CONNIE L · 2010 to 2013
$5.6M
Multi-component, Targeted HIV Prevention for sub-Saharan Africa: PreventionRxR01AI083034 · NIAID · UNIVERSITY OF WASHINGTON · PI CELUM, CONNIE L · 2009 to 2012
$4.3M
Prevention Umbrella for MSM in the AmericasR01AI083060 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI BUCHBINDER, SUSAN · 2009 to 2012
$3.7M
NIAID NIH HHS R01 AI083034NIAID NIH HHS R01 AI083034-02S2NIAID NIH HHS R01 AI083060NIAID NIH HHS R01AI083060-04NIAID NIH HHS RC4 AI092552NIAID NIH HHS UM1 AI068619NIAID NIH HHS UM1 AI069496
6 · The paper itself

Abstract

Combination HIV prevention is of high priority for increasing the impact of partially efficacious HIV prevention interventions for specific populations and settings. Developing the package requires critical review of local epidemiology of HIV infection regarding most-impacted populations and those at high risk of HIV transmission and acquisition, drivers of HIV infection, and available interventions to address these risk factors. Interventions should be considered in terms of the evidence basis for efficacy, potential synergies, and feasibility of delivery at scale, which is important to achieve high coverage and impact, coupled with high acceptability to populations, which will impact uptake, adherence, and retention. Evaluation requires process measures of uptake, adherence, retention, and outcome measures of reduction in HIV infectiousness and acquisition. Three examples of combination prevention concepts are summarized for men who have sex with men in the Americas, young women in sub-Saharan Africa, and HIV serodiscordant couples.

Indexed as

Africa South of the SaharaAmericasAnti-Retroviral AgentsFamily CharacteristicsFemaleHeterosexualityHIV InfectionsHomosexuality, MaleHumansMalePrimary PreventionRisk FactorsSexual BehaviorTransgender PersonsTreatment OutcomeAnti-Retroviral Agents

Identifiers

PMID23764638
PMCPMC3708491

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.