Evidence map›Paper›PMID 23763847›Full record

ArticleEmerging infectious diseases2013

Pneumococcal serotypes before and after introduction of conjugate vaccines, United States, 1999-2011(1.).

Sandra S Richter, Kristopher P Heilmann, Cassie L Dohrn, Fathollah Riahi, Daniel J Diekema, Gary V Doern

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  15. Efflux-Mediated Macrolide Resistance in ClinicalAntibiotics (Basel, Switzerland) · 2025
    Article
  16. Comparative Genotyping of Malaysian Clinical Isolates ofThe Malaysian journal of medical sciences : MJMS · 2025
    Article
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sandra S RichterCleveland Clinic, Cleveland, Ohio 44195, USA. richtes@ccf.org
Kristopher P Heilmann
Cassie L Dohrn
Fathollah Riahi
Daniel J Diekema
Gary V Doern

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotyping data for pneumococci causing invasive and noninvasive disease in 2008-2009 and 2010-2011 from >43 US centers were compared with data from preconjugate vaccine (1999-2000) and postconjugate vaccine (2004-2005) periods. Prevalence of 7-valent pneumococcal conjugate vaccine serotypes decreased from 64% of invasive and 50% of noninvasive isolates in 1999-2000 to 3.8% and 4.2%, respectively, in 2010-2011. Increases in serotype 19A stopped after introduction of 13-valent pneumococcal vaccine (PCV13) in 2010. Prevalences of other predominant serotypes included in or related to PCV13 (3, 6C, 7F) also remained similar for 2008-2009 and 2010-2011. The only major serotype that increased from 2008-2009 to 2010-2011 was nonvaccine serotype 35B. These data show that introduction of the 7-valent vaccine has dramatically decreased prevalence of its serotypes and that addition of serotypes in PCV13 could provide coverage of 39% of isolates that continue to cause disease.

Indexed as

Pneumococcal VaccinesVaccines, ConjugateAdolescentAdultAgedAge DistributionAnti-Bacterial AgentsChildChild, PreschoolCluster AnalysisHumansInfantMicrobial Sensitivity TestsMiddle AgedPenicillin ResistancePenicillins13-valent pneumococcal vaccineAnti-Bacterial AgentsPenicillinsPneumococcal VaccinesVaccines, Conjugatebacteriaconjugate vaccinespathogenesisserotypestreptococciStreptococcus pneumoniaeUnited Statesvaccine

Identifiers

PMID23763847
PMCPMC3713983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.