ArticleCase reports in psychiatry2013
Manic-like psychosis associated with elevated trough tacrolimus blood concentrations 17 years after kidney transplant.
Article in Case reports in psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- DeepBiomarker: Identifying Important Lab Tests from Electronic Medical Records for the Prediction of Suicide-Related Events among PTSD Patients.Journal of personalized medicine · 2022Article
- New-onset Psychosis in an Immunosuppressed Patient With Kidney Transplantation: An Educational Case Report.Canadian journal of kidney health and disease · 2020Article
- Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder.Scientific reports · 2019Article
- Decreased calcineurin immunoreactivity in the postmortem brain of a patient with schizophrenia who had been prescribed the calcineurin inhibitor, tacrolimus, for leukemia.Neuropsychiatric disease and treatment · 2016Article
- Immunosuppressant-associated neurotoxicity responding to olanzapine.Case reports in psychiatry · 2014Article
- Tacrolimus-induced mania in a patient with nephrotic syndrome.Indian journal of pharmacologyArticle
- When Paranoia Comes with the Treatment: Psychosis Associated with Tacrolimus Use.Case reports in nephrology and dialysisArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several neurological side effects induced by tacrolimus are described in the scientific literature, ranging from mild neurological symptoms to delirium and psychosis. We report the case of a 46-year-old man with no prior psychiatric history who suddenly manifested manic-like psychosis associated with elevated trough tacrolimus blood concentrations 17 years after kidney transplant. The use of antipsychotics may improve the severity of symptoms; but in order to obtain a complete remission, the reduction in the dose of tacrolimus, or its replacement with alternative immunosuppressant therapies, is recommended.
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Registered trials
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