ArticlePathobiology of aging & age related diseases2013
Fatal myocardial fibrosis in an aged chimpanzee (Pan troglodytes).
Article in Pathobiology of aging & age related diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Mitral Valve Dysplasia Leading to Congestive Heart Failure in a Male Squirrel Monkey (Animals : an open access journal from MDPI · 2026Article
- Discovery of novel biomarkers associated with myocardial fibrosis in chimpanzees (Frontiers in veterinary science · 2026Article
- Brain-type natriuretic peptide is a useful biomarker of cardiovascular disease and predictor of cardiac-related mortality in chimpanzees (Pan troglodytes).American journal of veterinary research · 2025Article
- Using the Welfare Quality® framework to develop a welfare assessment protocol for captive chimpanzees (Animal welfare (South Mimms, England) · 2025Review
- Transthoracic echocardiography and cardiac biomarkers in healthy captive male and female squirrel monkeys (Saimiri spp.).BMC veterinary research · 2020Article
- Neutrophil to Lymphocyte Ratio (NLR) in captive chimpanzees (Pan troglodytes): The effects of sex, age, and rearing.PloS one · 2020Article
- Thoracic radiography of healthy captive male and female Squirrel monkey (Saimiri spp.).PloS one · 2018Article
- Natural pathology of the captive chimpanzee (Pan troglodytes): A 35-year review.Journal of medical primatology · 2017Review
- Natural mortality and cause of death analysis of the captive chimpanzee (Pan troglodytes): A 35-year review.Journal of medical primatology · 2017Review
- Pauci-immune glomerulonephritis in a captive chimpanzee (Pan troglodytes), and a review of spontaneous cases in animals.Journal of medical primatology · 2016Review
- Use of an Implantable Loop Recorder in a Chimpanzee (Pan troglodytes) to Monitor Cardiac Arrhythmias and Assess the Effects of Acupuncture and Laser Therapy.Comparative medicine · 2016Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A 36-year-old male chimpanzee (Pan troglodytes) assigned to a life-long sign language communication project presented for sudden death. No other clinical or clinical pathological abnormalities were noted and given the signalment, death due to cardiac failure was suspected. Necropsy findings revealed moderate cardiomegaly and other chronic age-related findings including focal renal tubular cystic dilation and gingival hyperplasia. Histologic evaluation of the heart revealed interstitial fibrosing cardiomyopathy characterized by severe interstitial myocardial fibrosis replacing and separating myofibers within all chambers of the heart, especially the left ventricle, interventricular septum and subvalvular areas. This case report represents an additional case of sudden death associated with interstitial myocardial fibrosis in a chimpanzee. This process has been previously cited as the most common cause of sudden death in aged chimpanzees.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.