ArticlePloS one2013
Identification and characterization of the first Escherichia coli strain carrying NDM-1 gene in China.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Multidrug-resistant mammary pathogenicFrontiers in microbiology · 2026Article
- First Detection ofAntibiotics (Basel, Switzerland) · 2023Article
- High Genetic Diversity and Antimicrobial Resistance inMicroorganisms · 2022Article
- Molecular Characterization of KPC-2-ProducingAntibiotics (Basel, Switzerland) · 2021Article
- Population genomics and antimicrobial resistance dynamics of Escherichia coli in wastewater and river environments.Communications biology · 2021Article
- Coexistence of aminoglycoside resistance genes in CTX-M-producing isolates ofIranian journal of microbiology · 2021Article
- Emergence of High Level Carbapenem and Extensively Drug ResistantFrontiers in microbiology · 2021Article
- Corrigendum: First Report of Coexistence ofFrontiers in microbiology · 2021Article
- First Report of Coexistence ofFrontiers in microbiology · 2021Article
- Genetics of Acquired Antibiotic Resistance Genes inFrontiers in microbiology · 2020Review
- Bogotá River anthropogenic contamination alters microbial communities and promotes spread of antibiotic resistance genes.Scientific reports · 2019Article
- Fecal carriage and molecular epidemiology of carbapenem-resistant Enterobacteriaceae from outpatient children in Shanghai.BMC infectious diseases · 2019Article
- First Characterization of CTX-M-15-Producing Escherichia coli Strains Belonging to Sequence Type (ST) 410, ST224, and ST1284 from Commercial Swine in South America.Antimicrobial agents and chemotherapy · 2016Article
- First Report of Complete Sequence of aFrontiers in cellular and infection microbiology · 2016Article
- B1-Metallo-β-Lactamases: Where Do We Stand?Current drug targets · 2016Review
- Phenotypic Detection of Metallo-Beta-Lactamases in Carbapenem Resistant Acinetobacter baumannii Isolated from Pediatric Patients in Pakistan.Journal of pathogens · 2016Article
- Escherichia coli of sequence type 3835 carrying bla NDM-1, bla CTX-M-15, bla CMY-42 and bla SHV-12.Scientific reports · 2015Article
- New Delhi Metallo-β-Lactamase-Mediated Carbapenem Resistance: Origin, Diagnosis, Treatment and Public Health Concern.Chinese medical journal · 2015Review
- Acinetobacter calcoaceticus from a fatal case of pneumonia harboring bla(NDM-1) on a widely distributed plasmid.BMC infectious diseases · 2015Article
- Increasing resistance rate to carbapenem among blood culture isolates of Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa in a university-affiliated hospital in China, 2004-2011.The Journal of antibiotics · 2015Article
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Authors and funding
12 authors.
Funding
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Abstract
New Delhi metallo-β-lactamase-1 (NDM-1), an acquired class B carbapenemase, is a significant clinical threat due to its extended hydrolysis of β-lactams including carbapenems. In this study, we identified the first confirmed clinical isolate of Escherichia coli BJ01 harboring bla(NDM-1) in China. The isolate is highly resistant to all tested antimicrobials except polymyxin. bla(NDM-1), bla(CTX-M-57), and bla TEM-1 were identified in the isolate. bla(NDM-1) was transferable to E. coli EC600 and DH5α in both plasmid conjugation experiments and plasmid transformation tests. BJ01 was identified as a new sequence type, ST224, by multilocus sequence typing. Analysis of genetic environment shows complex transposon-like structures surrounding the bla NDM-1 gene. Genetic analysis revealed that the region flanking bla(NDM-1) was very similar to previously identified NDM-positive Acinetobacter spp. isolated in China. The findings of this study raise attention to the emergence and spread of NDM-1-carrying Enterobacteriaceae in China.
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