Evidence map›Paper›PMID 23762442›Full record

ArticlePloS one2013

Disability mediates the impact of common conditions on perceived health.

Jordi Alonso, Gemma Vilagut, Núria D Adroher, Somnath Chatterji, Yanling He, Laura Helena Andrade, Evelyn Bromet, Ronny Bruffaerts, John Fayyad, Silvia Florescu and 18 more

Erratum issuedAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Mental well-being of the general population: direct and indirect effects of socioeconomic, relational and health factors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

  • Erratum issued
    Hormel, J [corrected to Ormel, J Hans]
5 · Who and what money

Authors and funding

28 authors.

Jordi AlonsoIMIM-Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain ; Pompeu Fabra University, Barcelona, Spain. jalonso@imim.es
Gemma Vilagut
Núria D Adroher
Somnath Chatterji
Yanling He
Laura Helena Andrade
Evelyn Bromet
Ronny Bruffaerts
John Fayyad
Silvia Florescu
Giovanni de Girolamo
Oye Gureje
Josep Maria Haro
Hristo Hinkov
Chiyi Hu
Noboru Iwata
Sing Lee
Daphna Levinson
Jean Pierre Lépine
Herbert Matschinger
Maria Elena Medina-Mora
Siobhan O'Neill
J Hans Ormel
J Hormel
Jose A Posada-Villa
Nezar Ismet Taib
Miguel Xavier
Ronald C Kessler

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
COMORBID MENTAL DISORDERS IN PERIODS OF SOCIAL DISRUPTIOR01MH061905 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI BROMET, EVELYN J · 2000 to 2004
$1.7M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481FIC NIH HHS R03 TW006481-01NIDA NIH HHS R01 DA016558NIDA NIH HHS R01DA016558NIMH NIH HHS R01 MH061905NIMH NIH HHS R01 MH069864NIMH NIH HHS R01-MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R01MH070884NIMH NIH HHS R01-MH61905NIMH NIH HHS R13 MH066849NIMH NIH HHS R13-MH066849NIMH NIH HHS U01 MH060220NIMH NIH HHS U01-MH60220
6 · The paper itself

Abstract

backgroundWe examined the extent to which disability mediates the observed associations of common mental and physical conditions with perceived health. METHODS AND

findingsWHO World Mental Health (WMH) Surveys carried out in 22 countries worldwide (n = 51,344 respondents, 72.0% response rate). We assessed nine common mental conditions with the WHO Composite International Diagnostic Interview (CIDI), and ten chronic physical with a checklist. A visual analog scale (VAS) score (0, worst to 100, best) measured perceived health in the previous 30 days. Disability was assessed using a modified WHO Disability Assessment Schedule (WHODAS), including: cognition, mobility, self-care, getting along, role functioning (life activities), family burden, stigma, and discrimination. Path analysis was used to estimate total effects of conditions on perceived health VAS and their separate direct and indirect (through the WHODAS dimensions) effects. Twelve-month prevalence was 14.4% for any mental and 51.4% for any physical condition. 31.7% of respondents reported difficulties in role functioning, 11.4% in mobility, 8.3% in stigma, 8.1% in family burden and 6.9% in cognition. Other difficulties were much less common. Mean VAS score was 81.0 (SD = 0.1). Decrements in VAS scores were highest for neurological conditions (9.8), depression (8.2) and bipolar disorder (8.1). Across conditions, 36.8% (IQR: 31.2-51.5%) of the total decrement in perceived health associated with the condition were mediated by WHODAS disabilities (significant for 17 of 19 conditions). Role functioning was the dominant mediator for both mental and physical conditions. Stigma and family burden were also important mediators for mental conditions, and mobility for physical conditions.

conclusionsMore than a third of the decrement in perceived health associated with common conditions is mediated by disability. Although the decrement is similar for physical and mental conditions, the pattern of mediation is different. Research is needed on the benefits for perceived health of targeted interventions aimed at particular disability dimensions.

Indexed as

Activities of Daily LivingAdolescentAdultAgedAged, 80 and overFemaleHealth SurveysHumansMaleMental DisordersMiddle AgedPersons with DisabilitiesQuality of LifeSelf-AssessmentSelf Care

Identifiers

PMID23762442
PMCPMC3675077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.