ArticlePloS one2013
Lipid profiling demonstrates that suppressing Arabidopsis phospholipase Dδ retards ABA-promoted leaf senescence by attenuating lipid degradation.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 66 citations in OpenAlex.
- ABC1K2 is involved in stress response and secondary metabolism during seed development in Arabidopsis thaliana.Plant cell reports · 2025Article
- Unveiling the molecular mechanism underlying PSKR-mediated amplification of the ABA signaling in Arabidopsis thaliana.Plant cell reports · 2025Article
- Phospholipase-mediated phosphate recycling during plant leaf senescence.Genome biology · 2024Article
- Exploration of the pearl millet phospholipase gene family to identify potential candidates for grain quality traits.BMC genomics · 2024Article
- Influence of Nitrogen-Modified Atmosphere Storage on Lipid Oxidation of Peanuts: From a Lipidomic Perspective.Foods (Basel, Switzerland) · 2024Article
- Dissection of genetic architecture of nine hazardous component traits of mainstream smoke in tobacco (Frontiers in plant science · 2024Article
- Phosphatidic acid produced by phospholipase Dα1 and Dδ is incorporated into the internal membranes but not involved in the gene expression ofFrontiers in plant science · 2024Article
- Mapping-by-Sequencing Reveals Genomic Regions Associated with Seed Quality Parameters inGenes · 2022Article
- Impact of Plasma-Activated Water Treatment on Quality and Shelf-Life of Fresh Spinach Leaves Evaluated by Comprehensive Metabolomic Analysis.Foods (Basel, Switzerland) · 2021Article
- Chloroplast dismantling in leaf senescence.Journal of experimental botany · 2021Review
- Identification of two glycerophosphodiester phosphodiesterase genes in maize leaf phosphorus remobilization.The Crop journal · 2021Article
- Phospholipase Dα1 Acts as a Negative Regulator of High MgFrontiers in plant science · 2021Article
- The Serine Carboxypeptidase-Like GenePlants (Basel, Switzerland) · 2020Article
- Analysis of changes in thePlant diversity · 2020Article
- Secretion of Phospholipase Dδ Functions as a Regulatory Mechanism in Plant Innate Immunity.The Plant cell · 2019Article
- Abiotic Stresses Intervene with ABA Signaling to Induce Destructive Metabolic Pathways Leading to Death: Premature Leaf Senescence in Plants.International journal of molecular sciences · 2019Review
- Phospholipase D antagonist 1-butanol inhibited the mobilization of triacylglycerol during seed germination inPlant diversity · 2018Article
- Proteomic and Biochemical Changes during Senescence ofInternational journal of molecular sciences · 2018Article
- Article
- Profiling membrane glycerolipids during γ-ray-induced membrane injury.BMC plant biology · 2017Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Senescence is the last phase of the plant life cycle and has an important role in plant development. Degradation of membrane lipids is an essential process during leaf senescence. Several studies have reported fundamental changes in membrane lipids and phospholipase D (PLD) activity as leaves senesce. Suppression of phospholipase Dα1 (PLDα1) retards abscisic acid (ABA)-promoted senescence. However, given the absence of studies that have profiled changes in the compositions of membrane lipid molecules during leaf senescence, there is no direct evidence that PLD affects lipid composition during the process. Here, we show that application of n-butanol, an inhibitor of PLD, and N-Acylethanolamine (NAE) 12∶0, a specific inhibitor of PLDα1, retarded ABA-promoted senescence to different extents. Furthermore, phospholipase Dδ (PLDδ) was induced in leaves treated with ABA, and suppression of PLDδ retarded ABA-promoted senescence in Arabidopsis. Lipid profiling revealed that detachment-induced senescence had different effects on plastidic and extraplastidic lipids. The accelerated degradation of plastidic lipids during ABA-induced senescence in wild-type plants was attenuated in PLDδ-knockout (PLDδ-KO) plants. Dramatic increases in phosphatidic acid (PA) and decreases in phosphatidylcholine (PC) during ABA-induced senescence were also suppressed in PLDδ-KO plants. Our results suggest that PLDδ-mediated hydrolysis of PC to PA plays a positive role in ABA-promoted senescence. The attenuation of PA formation resulting from suppression of PLDδ blocks the degradation of membrane lipids, which retards ABA-promoted senescence.
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