ArticleEvidence-based complementary and alternative medicine : eCAM2013
Understanding central mechanisms of acupuncture analgesia using dynamic quantitative sensory testing: a review.
Article in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Effect of Electroacupuncture vs Sham Treatment on Change in Pain Severity Among Adults With Chronic Low Back Pain: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Laser acupuncture reduces pain in pediatric kidney biopsies: a randomized controlled trial.Pain · 2017Trial
- Pain sensitivity subgroups in individuals with spine pain: potential relevance to short-term clinical outcome.Physical therapy · 2014Trial
- Suprathreshold heat pain response predicts activity-related pain, but not rest-related pain, in an exercise-induced injury model.PloS one · 2014Trial
- The Potential of a Robot Presence in Close Relationship to Influence Human Responses to Experimental Pain.Life (Basel, Switzerland) · 2025Article
- Effect of Catastrophic Thinking on the Analgesic Effect of Electroacupuncture.Medical acupuncture · 2023Article
- Inhibition of current perception thresholds in A-delta and C fibers through somatosensory stimulation of the body surface.Scientific reports · 2022Article
- Caffeine Attenuates Electroacupuncture Effect on Pressure Pain Threshold and Tolerance in Healthy Individuals: A Randomized Controlled Trial.Frontiers in neurology · 2022Article
- The analgesic and sedative effects of GV20 pharmacopuncture with low-dose hydromorphone in healthy dogs undergoing ovariohysterectomy.The Canadian veterinary journal = La revue veterinaire canadienne · 2021Article
- Conditioned Pain Modulation (CPM) Effects Captured in Facial Expressions.Journal of pain research · 2021Article
- Association of Chronic Pain with Radiologic Severity and Central Sensitization in Hip Osteoarthritis Patients.Journal of pain research · 2021Article
- Electroacupuncture for Treating Chronic Low-Back Pain: Preliminary Research Results.Medical acupuncture · 2020Article
- High Temporal Summation of Pain Predicts Immediate Analgesic Effect of Acupuncture in Chronic Pain Patients-A Prospective Cohort Study.Frontiers in neuroscience · 2019Article
- Article
- The LURN Research Network Neuroimaging and Sensory Testing (NIST) Study: Design, protocols, and operations.Contemporary clinical trials · 2018Article
- Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing.Journal of visualized experiments : JoVE · 2017Article
- Ipsilateral Putamen and Insula Activation by Both Left and Right GB34 Acupuncture Stimulation: An fMRI Study on Healthy Participants.Evidence-based complementary and alternative medicine : eCAM · 2016Article
- Acupuncture Alleviated the Nonmotor Symptoms of Parkinson's Disease including Pain, Depression, and Autonomic Symptoms.Case reports in neurological medicine · 2014Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We discuss the emerging translational tools for the study of acupuncture analgesia with a focus on psychophysical methods. The gap between animal mechanistic studies and human clinical trials of acupuncture analgesia calls for effective translational tools that bridge neurophysiological data with meaningful clinical outcomes. Temporal summation (TS) and conditioned pain modulation (CPM) are two promising tools yet to be widely utilized. These psychophysical measures capture the state of the ascending facilitation and the descending inhibition of nociceptive transmission, respectively. We review the basic concepts and current methodologies underlying these measures in clinical pain research, and illustrate their application to research on acupuncture analgesia. Finally, we highlight the strengths and limitations of these research methods and make recommendations on future directions. The appropriate addition of TS and CPM to our current research armamentarium will facilitate our efforts to elucidate the central analgesic mechanisms of acupuncture in clinical populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.