ArticleInternational journal of endocrinology2013
Relation of epicardial fat thickness with carotid intima-media thickness in patients with type 2 diabetes mellitus.
Article in International journal of endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epicardial fat tissue in patients with diabetes mellitus: a systematic review and meta-analysis.Cardiovascular diabetology · 2019Pooled it
- Effects of Hormone Therapy on Heart Fat and Coronary Artery Calcification Progression: Secondary Analysis From the KEEPS Trial.Journal of the American Heart Association · 2019Trial
- Combined assessment of carotid intima-media thickness and epicardial fat thickness for cardiovascular risk stratification in asymptomatic South Indian adults.Frontiers in cardiovascular medicine · 2026Article
- Predictive Value of Epicardial Adipose Tissue Thickness for Plaque Vulnerability in Left Coronary Arteries: Histological Evidence from 245 Sudden Cardiac Death Cases.Diagnostics (Basel, Switzerland) · 2025Article
- Remodeling of the Intracardiac Ganglia During the Development of Cardiovascular Autonomic Dysfunction in Type 2 Diabetes: Molecular Mechanisms and Therapeutics.International journal of molecular sciences · 2024Review
- Review
- Fetal Epicardial Fat Thickness: Its Role as Marker for Gestational Diabetic Mellitus.The Indian journal of radiology & imaging · 2023Article
- Targeting epicardial adipose tissue: A potential therapeutic strategy for heart failure with preserved ejection fraction with type 2 diabetes mellitus.World journal of diabetes · 2023Review
- Potential impact of epicardial fat thickness, pentraxin-3, and high-sensitive C-reactive protein on the risk of non-proliferative diabetic retinopathy.Journal of diabetes and metabolic disorders · 2023Article
- Pre-diabetes is associated with attenuation rather than volume of epicardial adipose tissue on computed tomography.Scientific reports · 2023Article
- Dysregulated Epicardial Adipose Tissue as a Risk Factor and Potential Therapeutic Target of Heart Failure with Preserved Ejection Fraction in Diabetes.Biomolecules · 2022Review
- Identification of key genes and mechanisms of epicardial adipose tissue in patients with diabetes through bioinformatic analysis.Frontiers in cardiovascular medicine · 2022Article
- Article
- The relationship between epicardial fat tissue thickness and transit time flow measurement values of coronary artery bypass grafts.Journal of cardiovascular and thoracic research · 2020Article
- Is elevated urotensin II level a predictor for increased cardiovascular risk in subjects with acromegaly?Journal of endocrinological investigation · 2019Article
- Atherosclerosis in chronic hepatitis C virus patients with and without liver cirrhosis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2017Article
- Clinical importance of epicardial adipose tissue.Archives of medical science : AMS · 2017 · on this mapArticle
- Epicardial fat: a novel marker of subclinical atherosclerosis in clinical practice?Anatolian journal of cardiology · 2017Article
- Serum paraoxonase activity is associated with epicardial fat tissue in renal transplant recipients.International urology and nephrology · 2015Article
- Local and systemic effects of the multifaceted epicardial adipose tissue depot.Nature reviews. Endocrinology · 2015 · on this mapReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims. The aim of this study was to investigate the relationship of echocardiographic epicardial fat thickness (EFT) with carotid intima-media thickness (CIMT), in patients with type 2 diabetes mellitus (T2DM). Methods and Results. A total of 139 patients with T2DM (mean age 54.3 ± 9.2 and 49.6% male) and 40 age and sex-matched control subjects were evaluated. Echocardiographic EFT and ultrasonographic CIMT were measured in all subjects. Patients with T2DM had significantly increased EFT and CIMT than those of the controls (6.0 ± 1.5 mm versus 4.42 ± 1.0 mm, P < 0.001 and 0.76 ± 0.17 mm versus 0.57 ± 0.14 mm, P < 0.001, resp.). EFT was correlated with CIMT, waist circumference, BMI, age, duration of T2DM, HbA1c in the type 2 diabetic patients. Linear regression analysis showed that CIMT (β = 3.52, t = 3.72, P < 0.001) and waist circumference (β = 0.36, t = 2.26, P = 0.03) were found to be independent predictors of EFT. A cutoff high risk EFT value of 6.3 mm showed a sensitivity and specificity of 72.5% and 71.7%, respectively, for the prediction of subclinical atherosclerosis. Conclusion. We found that echocardiographic EFT was significantly higher in patients with T2DM. Our study also showed that EFT was strongly correlated with waist circumference and CIMT as being independent of sex.
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