Evidence map›Paper›PMID 23762048›Full record

ArticleJournal of toxicology2013

Cumulative risk assessment toolbox: methods and approaches for the practitioner.

Margaret M Macdonell, Lynne A Haroun, Linda K Teuschler, Glenn E Rice, Richard C Hertzberg, James P Butler, Young-Soo Chang, Shanna L Clark, Alan P Johns, Camarie S Perry and 3 more

Abstract read
In one paragraph

Article in Journal of toxicology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Framing Environmental Health Decision-Making: The Struggle over Cumulative Impacts Policy.International journal of environmental research and public health · 2021
    Article
  5. Evolving Science and Practice of Risk Assessment.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  6. Article
  7. A Cumulative Risk Perspective for Occupational Health and Safety (OHS) Professionals.International journal of environmental research and public health · 2020
    Article
  8. Article
  9. Characterizing Risk for Cumulative Risk Assessments.Risk analysis : an official publication of the Society for Risk Analysis · 2018
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Margaret M MacdonellEnvironmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USA.
Lynne A Haroun
Linda K Teuschler
Glenn E Rice
Richard C Hertzberg
James P Butler
Young-Soo Chang
Shanna L Clark
Alan P Johns
Camarie S Perry
Shannon S Garcia
John H Jacobi
Marcienne A Scofield

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The historical approach to assessing health risks of environmental chemicals has been to evaluate them one at a time. In fact, we are exposed every day to a wide variety of chemicals and are increasingly aware of potential health implications. Although considerable progress has been made in the science underlying risk assessments for real-world exposures, implementation has lagged because many practitioners are unaware of methods and tools available to support these analyses. To address this issue, the US Environmental Protection Agency developed a toolbox of cumulative risk resources for contaminated sites, as part of a resource document that was published in 2007. This paper highlights information for nearly 80 resources from the toolbox and provides selected updates, with practical notes for cumulative risk applications. Resources are organized according to the main elements of the assessment process: (1) planning, scoping, and problem formulation; (2) environmental fate and transport; (3) exposure analysis extending to human factors; (4) toxicity analysis; and (5) risk and uncertainty characterization, including presentation of results. In addition to providing online access, plans for the toolbox include addressing nonchemical stressors and applications beyond contaminated sites and further strengthening resource accessibility to support evolving analyses for cumulative risk and sustainable communities.

Identifiers

PMID23762048
PMCPMC3665252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.