Evidence map›Paper›PMID 23761962›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2013

Results of case-control studies support the association between contact lens use and Acanthamoeba keratitis.

Elena Pacella, Giuseppe La Torre, Maria De Giusti, Chiara Brillante, Anna Maria Lombardi, Gianpaolo Smaldone, Tommaso Lenzi, Fernanda Pacella

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Epidemiology of and Genetic Factors Associated withPathogens (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Pathogens (Basel, Switzerland) · 2021
    Review
  6. Intracellular Microbiome Profiling of thePathogens (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elena PacellaDepartment of Sense Organs, Faculty of Medicine and Dentistry, Sapienza University of Rome, Italy.
Giuseppe La Torre
Maria De Giusti
Chiara Brillante
Anna Maria Lombardi
Gianpaolo Smaldone
Tommaso Lenzi
Fernanda Pacella
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcanthamoeba keratitis (AK) is ever more frequently reported in industrialized countries. The loss of the corneal surface integrity consequent to secondary microtrauma produced by the use of contact lens (CL) favors the penetration of the parasite into the corneal tissue.

objectivesA scientific review was performed to investigate the association of CL wear as an Acanthamoeba keratitis (AK) risk factor.

methodsA computerized screening of 7834 Medline articles (4623 from PubMed; 3211 from Scopus) used a strict selection criteria of case-control studies involving CL wear and/or trauma.

resultsThe search yielded five case-control studies published from 1995 to 2012. All studies included showed a statistically significant positive association between AK and CL use, with a combined odds ratio (OR) of 10.21 (95%, confidence intervals [CI]; 3.57-27.64). STATISTICAL ANALYSIS: All studies included showed a statistically significant positive association between AK and CL use, though with differing OR values.

conclusionThough rare, AK should be held in higher consideration when ophthalmologists are faced with CL users exhibiting simplex-like lesions associated with circular stromal infiltrates and disproportionate ocular pain in respect to the objective clinical picture.

Indexed as

Acanthamoebacontact lenskeratitis

Identifiers

PMID23761962
PMCPMC3673962
OpenAlexW2043375427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.