ArticleJournal of neurophysiology2013
Modulation of central gustatory coding by temperature.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Stimulus temperature modulates the psychophysical dimensions of salt taste.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Temperature effects on taste preferences are influenced by TRPM8.bioRxiv : the preprint server for biology · 2026Article
- Electrophysiological responses to appetitive and consummatory behavior in the rostral nucleus tractus solitarius in awake, unrestrained rats.bioRxiv : the preprint server for biology · 2024Article
- Separation of Oral Cooling and Warming Requires TRPM8.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Electrophysiological responses to appetitive and consummatory behavior in the rostral nucleus tractus solitarius in awake, unrestrained rats.Frontiers in integrative neuroscience · 2024Article
- Effects of temperature on action potentials and ion conductances in type II taste-bud cells.American journal of physiology. Cell physiology · 2023Article
- Oral thermal processing in the gustatory cortex of awake mice.Chemical senses · 2023Article
- From receptors to the brain: Psychophysical clues to taste physiology.Current opinion in physiology · 2021Article
- Cortical Hub for Flavor Sensation in Rodents.Frontiers in systems neuroscience · 2021Review
- Cortical processing of chemosensory and hedonic features of taste in active licking mice.Journal of neurophysiology · 2020Article
- Sweet Thermal Taste: Perceptual Characteristics in Water and Dependence on TAS1R2/TAS1R3.Chemical senses · 2020Article
- Single and population coding of taste in the gustatory cortex of awake mice.Journal of neurophysiology · 2019Article
- Selective Effects of Temperature on the Sensory Irritation but not Taste of NaCl and Citric Acid.Chemical senses · 2019Article
- Central taste anatomy and physiology.Handbook of clinical neurology · 2019Review
- Modulation of taste processing by temperature.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Review
- Stimulus-Dependent Effects of Temperature on Bitter Taste in Humans.Chemical senses · 2017Article
- Immunocytochemical organization and sour taste activation in the rostral nucleus of the solitary tract of mice.The Journal of comparative neurology · 2017Article
- Taste coding of complex naturalistic taste stimuli and traditional taste stimuli in the parabrachial pons of the awake, freely licking rat.Journal of neurophysiology · 2016Article
- The Effect of Temperature on Umami Taste.Chemical senses · 2016Article
- Separate functions for responses to oral temperature in thermo-gustatory and trigeminal neurons.Chemical senses · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Changes in oral temperature can influence taste perception, indicating overlap among mechanisms for taste and oral somesthesis. Medullary gustatory neurons can show cosensitivity to temperature, albeit how these cells process combined taste and thermal input is poorly understood. Here, we electrophysiologically recorded orosensory responses (spikes) from 39 taste-sensitive neurons in the nucleus tractus solitarii of anesthetized mice during oral delivery of tastants adjusted to innocuous cool (16 and 18°C), room (22°C, baseline), and warm (30 and 37°C) oral temperatures. Stimuli included (in mM) 100 sucrose, 30 NaCl, 3 HCl, 3 quinine, an umami mixture, and water. Although cooled water excited few cells, water warmed to 30 and 37°C significantly excited 33% and 64% of neurons, respectively. Warmth induced responses of comparable magnitude to room temperature tastants. Furthermore, warming taste solutions influenced the distribution of gustatory responses among neurons and increased (P < 0.05) neuronal breadth of tuning across taste qualities. The influence of warmth on response magnitude was stimulus specific. Across neurons, warming facilitated responses to sucrose and umami in a superadditive manner, as these responses exceeded (P < 0.05) the arithmetic sum of activity to warming alone and the taste stimulus tested at room temperature. Superadditive increases (P < 0.05) in responding were also noted in some cells for warmed HCl. Yet warming induced only simple additive or subtractive effects on responses to quinine and NaCl. Data show temperature is a parameter of gustatory processing, like taste quality and concentration, in medullary circuits for taste.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.