Evidence map›Paper›PMID 23761683›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Multiscale segmentation of the skull in MR images for MRI-based attenuation correction of combined MR/PET.

Xiaofeng Yang, Baowei Fei

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. MRI classification using semantic random forest with auto-context model.Quantitative imaging in medicine and surgery · 2021
    Article
  4. Review
  5. Review
  6. Machine learning in quantitative PET: A review of attenuation correction and low-count image reconstruction methods.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Pseudo CT Estimation from MRI Using Patch-based Random Forest.Proceedings of SPIE--the International Society for Optical Engineering · 2017
    Article
  12. Review
  13. Review
  14. Trends in biomedical informatics: automated topic analysis of JAMIA articles.Journal of the American Medical Informatics Association : JAMIA · 2015
    Article
  15. Article
  16. A Minimum Spanning Forest Based Hyperspectral Image Classification Method for Cancerous Tissue Detection.Proceedings of SPIE--the International Society for Optical Engineering · 2014
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Xiaofeng YangDepartment of Radiology and Imaging Sciences, Center for Systems Imaging, Emory University, Atlanta, Georgia, USA.
Baowei Fei
Emory University · USGeorgia Institute of Technology · US

Funding

uPAR Targeted in Vivo Molecular Magnetic Resonance Imaging of....P50CA128301 · NCI · EMORY UNIVERSITY · PI SCHUSTER, DAVID MICHAEL · 2008 to 2012
$6.8M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
NCI NIH HHS P50 CA128301NCI NIH HHS P50CA128301NCI NIH HHS R01 CA156775NCI NIH HHS R01CA156775
6 · The paper itself

Abstract

BACKGROUND AND

objectiveCombined magnetic resonance/positron emission tomography (MR/PET) is a relatively new, hybrid imaging modality. MR-based attenuation correction often requires segmentation of the bone on MR images. In this study, we present an automatic segmentation method for the skull on MR images for attenuation correction in brain MR/PET applications. MATERIALS AND

methodsOur method transforms T1-weighted MR images to the Radon domain and then detects the features of the skull image. In the Radon domain we use a bilateral filter to construct a multiscale image series. For the repeated convolution we increase the spatial smoothing in each scale and make the width of the spatial and range Gaussian function doubled in each scale. Two filters with different kernels along the vertical direction are applied along the scales from the coarse to fine levels. The results from a coarse scale give a mask for the next fine scale and supervise the segmentation in the next fine scale. The use of the multiscale bilateral filtering scheme is to improve the robustness of the method for noise MR images. After combining the two filtered sinograms, the reciprocal binary sinogram of the skull is obtained for the reconstruction of the skull image.

resultsThis method has been tested with brain phantom data, simulated brain data, and real MRI data. For real MRI data the Dice overlap ratios are 92.2%±1.9% between our segmentation and manual segmentation.

conclusionsThe multiscale segmentation method is robust and accurate and can be used for MRI-based attenuation correction in combined MR/PET.

Indexed as

BrainDiagnosis, Computer-AssistedHumansMagnetic Resonance ImagingMathematical ConceptsPhantoms, ImagingPositron-Emission TomographySkullAttenuation correctionCombined MR/PETImage segmentationMultimodality Imagingmultiscale bilateral filterRadon transform

Identifiers

PMID23761683
PMCPMC3822115
OpenAlexW224483403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.