Evidence map›Paper›PMID 23761161›Full record

ArticlePeerJ2013

What is the "normal" fetal heart rate?

Stephanie Pildner von Steinburg, Anne-Laure Boulesteix, Christian Lederer, Stefani Grunow, Sven Schiermeier, Wolfgang Hatzmann, Karl-Theodor M Schneider, Martin Daumer

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PeerJ, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04043299 (Birth Asphyxia in Uganda), which is not on this map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
11.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04043299 phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

Birth Asphyxia in Uganda: Prevalence, Associated Factors and Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes

TypeinterventionalSponsorMakerere UniversityRan2020 to 2020Enrolled1,108ConditionsFetal Distress, Birth AsphyxiaArms100% Oxygen, 21% oxygen
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 136 citations in OpenAlex.

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  12. Fetal Health Prediction From Cardiotocography Recordings Using Kolmogorov-Arnold Networks.IEEE open journal of engineering in medicine and biology · 2025
    Article
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  16. Diagnosis and Management of Fetal Arrhythmias in the Current Era.Journal of cardiovascular development and disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Stephanie Pildner von SteinburgFrauenklinik und Poliklinik der Technischen Universität München , Munich , Germany.
Anne-Laure Boulesteix
Christian Lederer
Stefani Grunow
Sven Schiermeier
Wolfgang Hatzmann
Karl-Theodor M Schneider
Martin Daumer
Klinikum rechts der Isar · DESylvia Lawry Centre for Multiple Sclerosis Research · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim. There is no consensus about the normal fetal heart rate. Current international guidelines recommend for the normal fetal heart rate (FHR) baseline different ranges of 110 to 150 beats per minute (bpm) or 110 to 160 bpm. We started with a precise definition of "normality" and performed a retrospective computerized analysis of electronically recorded FHR tracings. Methods. We analyzed all recorded cardiotocography tracings of singleton pregnancies in three German medical centers from 2000 to 2007 and identified 78,852 tracings of sufficient quality. For each tracing, the baseline FHR was extracted by eliminating accelerations/decelerations and averaging based on the "delayed moving windows" algorithm. After analyzing 40% of the dataset as "training set" from one hospital generating a hypothetical normal baseline range, evaluation of external validity on the other 60% of the data was performed using data from later years in the same hospital and externally using data from the two other hospitals. Results. Based on the training data set, the "best" FHR range was 115 or 120 to 160 bpm. Validation in all three data sets identified 120 to 160 bpm as the correct symmetric "normal range". FHR decreases slightly during gestation. Conclusions. Normal ranges for FHR are 120 to 160 bpm. Many international guidelines define ranges of 110 to 160 bpm which seem to be safe in daily practice. However, further studies should confirm that such asymmetric alarm limits are safe, with a particular focus on the lower bound, and should give insights about how to show and further improve the usefulness of the widely used practice of CTG monitoring.

Indexed as

BaselineCardiotocographyComputerized analysisFetal heart rateGuidelinesMonitoring

Identifiers

PMID23761161
PMCPMC3678114
OpenAlexW2160033581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.