Evidence map›Paper›PMID 23760634›Full record

Trial reportAIDS and behavior2013

Test of a web-based program to improve adherence to HIV medications.

Rebekah K Hersch, Royer F Cook, Douglas W Billings, Seth Kaplan, David Murray, Steven Safren, Justin Goforth, Joy Spencer

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 7 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 7 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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  14. Leveraging virtual reality to improve medication adherence among marginalized populations with high-risk chronic health conditions: Proof-of-concept protocol, considerations, and next steps.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Rebekah K HerschISA Associates, Inc., 201 North Union Street, Suite 330, Alexandria, VA, 22304, USA, rhersch@isagroup.com.
Royer F Cook
Douglas W Billings
Seth Kaplan
David Murray
Steven Safren
Justin Goforth
Joy Spencer
ISA Associate · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USGeorge Mason University · USMassachusetts General Hospital · USWhitman-Walker Health · US

Funding

Test of a Web-Based Program to Improve Adherence to HIV/AIDS MedicationsRC1DA028505 · NIDA · ISA ASSOCIATES, INC. · PI COOK, ROYER F · 2009 to 2010
$993k
NIDA NIH HHS 5RC1DA028505NIDA NIH HHS RC1 DA028505
6 · The paper itself

Abstract

We evaluated the effectiveness of a web-based version of the Life-Steps intervention combined with modules for stress reduction and mood management, designed to improve medication adherence among HIV infected individuals. 168 HIV+ adults were randomized into either the Life-Steps program or a waitlist control condition. All participants completed a baseline assessment and provided a 2-week electronic pill (MEMS) cap baseline reading. Follow up data collection was conducted at 3, 6 and 9 months. Patients in the web-based Life-Steps condition had significantly higher antiretroviral medication adherence rates than patients in the control group over the nine-month period as measured by the MEMS cap. In addition, analysis of viral load data indicated that the program also resulted in a significant decrease in viral load. These findings indicate that a web-based Life-Steps program can be a useful and implementable tool for helping patients living with HIV maintain medication adherence.

Indexed as

Drug MonitoringInternetViral LoadAdultAffectAgedAnti-HIV AgentsEvidence-Based MedicineFemaleFollow-Up StudiesHealth PromotionHIV InfectionsHumansMaleMedication AdherenceMiddle AgedAnti-HIV Agents

Identifiers

PMID23760634
PMCPMC3812347
OpenAlexW1976457587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.