ArticleThe Indian journal of medical research2013
A study of aetiology of portal hypertension in adults (including the elderly) at a tertiary centre in southern India.
Article in The Indian journal of medical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Management of Portal Hypertension in the Older Patient.Current gastroenterology reports · 2024Review
- Ectopic variceal bleeding from chronic superior mesenteric vein thrombosis after hemorrhagic pancreatitis.Clinical case reports · 2022Article
- Ultrasonographic Determination of Portal Vein Diameter Among Adults with and without Chronic Liver Disease at Selected Referral Hospitals in Southern Ethiopia.International journal of general medicine · 2022Article
- Liver disease accompanied by enteropathy in common variable immunodeficiency: Common pathophysiological mechanisms.Frontiers in immunology · 2022Article
- An Update on the Management of Budd-Chiari Syndrome.Digestive diseases and sciences · 2021Review
- Cirrhotic patients and older people.World journal of hepatology · 2019Review
- What makes non-cirrhotic portal hypertension a common disease in India? Analysis for environmental factors.The Indian journal of medical research · 2019Review
- Coeliac disease as a potential cause of idiopathic portal hypertension: a case report.Gastroenterology report · 2018Article
- Idiopathic portal hypertension and extrahepatic portal venous obstruction.Hepatology international · 2018Review
- Maintenance zinc therapy after initial penicillamine chelation to treat symptomatic hepatic Wilson's disease in resource constrained setting.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018Article
- Current Scenario of Hepatitis B and Its Treatment in India.Journal of clinical and translational hepatology · 2017Review
- ADAMTS13 missense variants associated with defective activity and secretion of ADAMTS13 in a patient with non-cirrhotic portal hypertension.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017Article
- Arsenicosis, possibly from contaminated groundwater, associated with noncirrhotic intrahepatic portal hypertension.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2016Article
- Indications of Liver Biopsy in the Era of Noninvasive Assessment of Liver Fibrosis.Journal of clinical and experimental hepatology · 2015Article
- Investigation into celiac disease in Indian patients with portal hypertension.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2014Article
- Idiopathic Non-Cirrhotic Intrahepatic Portal Hypertension (NCIPH)-Newer Insights into Pathogenesis and Emerging Newer Treatment Options.Journal of clinical and experimental hepatology · 2014Review
- Spectrum of chronic liver disease admitted to a medical college hospital in northern India: is there cause for concern?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2014Article
- ADAMTS13 deficiency, despite well-compensated liver functions in patients with noncirrhotic portal hypertension.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2014Article
- Noncirrhotic intrahepatic portal hypertension: towards a unifying definition and etiology.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2014Article
- Prevalence of Risk Factors for Nonalcoholic Fatty Liver Disease in Middle-Aged and Elderly Patients With Cryptogenic Cirrhosis.Journal of clinical and experimental hepatologyArticle
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesThere are only a few studies on aetiology of portal hypertension among adults presenting to tertiary care centres in India; hence we conducted this study to assess the aetiological reasons for portal hypertension in adult patients attending a tertiary care centre in southern India.
methodsCauses of portal hypertension were studied in consecutive new adult patients with portal hypertension attending department of Hepatatology at a tertiary care centre in south India during July 2009 to July 2010.
resultsA total of 583 adult patients (>18 yr old) were enrolled in the study. After non-invasive testing, commonest causes of portal hypertension were cryptogenic chronic liver disease (35%), chronic liver disease due to alcohol (29%), hepatitis B (17%) or hepatitis C (9%). Of the 203 patients with cryptogenic chronic liver disease, 39 had liver biopsy - amongst the latter, idiopathic non cirrhotic intrahepatic portal hypertension (NCIPH) was seen in 16 patients (41%), while five patients had cirrhosis due to non alcoholic fatty liver disease. Fifty six (10%) adult patients with portal hypertension had vascular liver disorders. Predominant causes of portal hypertension in elderly (>60 yrs; n=83) were cryptogenic chronic liver disease (54%) and alcohol related chronic liver disease (16%). INTERPRETATION &
conclusionsCryptogenic chronic liver disease was the commonest cause of portal hypertension in adults, followed by alcohol or hepatitis B related chronic liver disease. Of patients with cryptogenic chronic liver disease who had liver biopsy, NCIPH was the commonest cause identified. Vascular liver disorders caused portal hypertension in 10 per cent of adult patients. Cryptogenic chronic liver disease was also the commonest cause in elderly patients.
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Identifiers
23760378PMC3734684W2107750075What OpenQuestion holds
Registered trials
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