ArticleOrganic & biomolecular chemistry2013
Various cyclization scaffolds by a truly Ugi 4-CR.
Article in Organic & biomolecular chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- The status of isocyanide-based multi-component reactions in Iran (2010-2018).Molecular diversity · 2021Review
- Crystal structure ofActa crystallographica. Section E, Crystallographic communications · 2021Article
- The Pictet-Spengler Reaction Updates Its Habits.Molecules (Basel, Switzerland) · 2020Review
- One-pot synthesis of novel 1-(1H-tetrazol-5-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine derivatives via an Ugi-azide 4CR process.Molecular diversity · 2018Article
- Two-Step Macrocycle Synthesis by Classical Ugi Reaction.The Journal of organic chemistry · 2018Article
- With unprotected amino acids to tetrazolo peptidomimetics.Chemical communications (Cambridge, England) · 2017Article
- Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations.ACS combinatorial science · 2017Article
- Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation.Molecular diversity · 2016Article
- MCR synthesis of a tetracyclic tetrazole scaffold.Bioorganic & medicinal chemistry · 2015Article
- Efficient isocyanide-less isocyanide-based multicomponent reactions.Organic letters · 2015Article
- Focusing on shared subpockets - new developments in fragment-based drug discovery.Expert opinion on drug discovery · 2015Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Efficient access to a large chemical space based on new scaffolds with defined 3D conformations and highly variable in the side chains is needed to find novel functional materials. Four heterocyclic scaffolds based on a four component Ugi reaction of α-amino acids, oxo components, isocyanides and primary or secondary amines suitably functionalized are described. A handful of examples are described for each scaffold.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.