ArticleMolecules (Basel, Switzerland)2013
[Fe₂L₃]⁴⁺ cylinders derived from bis(bidentate) 2-pyridyl-1,2,3-triazole "click" ligands: synthesis, structures and exploration of biological activity.
Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
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- Optimizing Intracellular Transport of Antimicrobial Metallohelices Delivers Selective Nanomolar Potency inInorganic chemistry · 2026Article
- Selective Sequestration of Palladium(II) Cations Using a Supramolecular Polymer Approach.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Low-Symmetry Face-Capped Fe(II) Tetrahedra Through Anisotropic Ligand Extension.Angewandte Chemie (International ed. in English) · 2025Article
- Dicobalt(ii) helices kill colon cancer cellsChemical science · 2024Article
- Synthesis and crystal structure of a PdIUCrData · 2023Article
- Metallohelices emulate the properties of short cationic α-helical peptides.Chemical science · 2021Review
- Cavity-Containing [FeFrontiers in chemistry · 2021Article
- Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo.Angewandte Chemie (International ed. in English) · 2020Article
- Article
- Computational investigations of click-derived 1,2,3-triazoles as keystone ligands for complexation with transition metals: a review.RSC advances · 2018Review
- Biomedical Applications of Metallosupramolecular Assemblies-Structural Aspects of the Anticancer Activity.Frontiers in chemistry · 2018Review
- Self-Assembly with 2,6-Bis(1-(pyridin-4-ylmethyl)-1H-1,2,3-triazol-4-yl)pyridine: Silver(I) and Iron(II) Complexes.Molecules (Basel, Switzerland) · 2017Article
- Oxidatively Locked [Co₂L₃]Molecules (Basel, Switzerland) · 2016Article
- Crystal structure of tris-(μ-bis-{4-[(pyridin-2-yl-methyl-idene)amino]-phen-yl}methane-κ(4) N,N':N'',N''')dizinc tetra-kis-(tetra-fluorido-borate) aceto-nitrile tris-olvate.Acta crystallographica. Section E, Crystallographic communications · 2015Article
- Non-equilibrium cobalt(iii) "click" capsules.Chemical science · 2015Article
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9 authors.
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Abstract
A series of metallosupramolecular [Fe₂L₃](BF₄)₄ "click" cylinders have been synthesized in excellent yields (90%-95%) from [Fe(H₂O)₆](BF₄)₂ and bis(bidentate) pyridyl-1,2,3-triazole ligands. All complexes were characterized by elemental analysis, IR, UV-vis, ¹H-, ¹³C- and DOSY-NMR spectroscopies and, in four cases, the structures confirmed by X-ray crystallography. Molecular modeling indicated that some of these "click" complexes were of similar size and shape to related biologically active pyridylimine-based iron(II) helicates and suggested that the "click" complexes may bind both duplex and triplex DNA. Cell-based agarose diffusion assays showed that the metallosupramolecular [Fe₂L₃](BF₄)₄ "click" cylinders display no antifungal activity against S. cerevisiae. This observed lack of antifungal activity appears to be due to the poor stability of the "click" complexes in DMSO and biological media.
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