Evidence map›Paper›PMID 23759452›Full record

ArticleThe Journal of clinical psychiatry2013

Modeling trajectory of depressive symptoms among psychiatric inpatients: a latent growth curve approach.

Joshua D Clapp, Anouk L Grubaugh, Jon G Allen, Jane Mahoney, John M Oldham, J Christopher Fowler, Tom Ellis, Jon D Elhai, B Christopher Frueh

Abstract read
In one paragraph

Article in The Journal of clinical psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  3. Prediction of short-term antidepressant response using probabilistic graphical models with replication across multiple drugs and treatment settings.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Joshua D ClappDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA. jclapp@uwyo.edu
Anouk L Grubaugh
Jon G Allen
Jane Mahoney
John M Oldham
J Christopher Fowler
Tom Ellis
Jon D Elhai
B Christopher Frueh
Menninger Clinic · USBaylor College of Medicine · USMedical University of South Carolina · USRalph H. Johnson VA Medical Center · USUniversity of Toledo · US

Funding

Traumatic Stress Across the Lifespan: A Biopsychosocial Training ProgramT32MH018869 · NIMH · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CARLA KMETT DANIELSON, DEAN Gaines KILPATRICK · 1988 to 2026
$7.2M
NIMH NIH HHS T32 MH018869NIMH NIH HHS T32 MH18869
6 · The paper itself

Abstract

objectiveChanges in the parameters of inpatient psychiatric care have inspired a sizable literature exploring correlates of prolonged intervention as well as symptom change over varying lengths of hospitalization. However, existing data offer limited insight regarding the nature of symptom change over time. Objectives of this longitudinal research were to (1) model the trajectory of depressive symptoms within an inpatient psychiatric sample, (2) identify characteristics associated with unique patterns of change, and (3) evaluate the magnitude of expected gains using objective clinical benchmarks.

methodParticipants included 1,084 psychiatric inpatients treated between April 2008 and December 2010. Latent growth curve modeling was used to determine the trajectory of Beck Depression Inventory II depressive symptoms in response to treatment. Age, gender, trauma history, prior hospitalization, and DSM-IV diagnoses were examined as potential moderators of recovery.

resultsResults indicate a nonlinear model of recovery, with symptom reductions greatest following admission and slowing gradually over time. Female gender, probable trauma exposure, prior psychiatric hospitalization, and primary depressive diagnosis were associated with more severe trajectories. Diagnosis of alcohol/substance use, by contrast, was associated with more moderate trajectories. Objective benchmarks occurred relatively consistently across patient groups, with clinically significant change occurring between 2-4 weeks after admission.

conclusionsThe nonlinear trajectory of recovery observed in these data provides insight regarding the dynamics of inpatient recovery. Across all patient groups, symptom reduction was most dramatic in the initial week of hospitalization. However, notable improvement continued for several weeks after admission. Results suggest that timelines for adequate inpatient care are largely contingent on program-specific goals.

Indexed as

DepressionHospitals, PsychiatricInpatientsModels, PsychologicalAdultFemaleHumansMaleMiddle AgedPsychiatric Status Rating ScalesTime FactorsTreatment Outcome

Identifiers

PMID23759452
PMCPMC4313384
OpenAlexW2027615607

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.