Evidence map›Paper›PMID 23759067›Full record

ArticleAntimicrobial resistance and infection control2013

Carriage of extended-spectrum beta-lactamase-producing enterobacteriacae among internal medicine patients in Switzerland.

Janet Pasricha, Thibaud Koessler, Stephan Harbarth, Jacques Schrenzel, Véronique Camus, Gilles Cohen, Arnaud Perrier, Didier Pittet, Anne Iten

Abstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in Antimicrobial resistance and infection control, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

11citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

Antibiotic-resistant pathogens in different patient settings and identification of surveillance gaps in Switzerland - a systematic review.Epidemiology and infection · 2019
Pooled it
Modelling and Simulation of the Effect of Targeted Decolonisation on Incidence of Extended-Spectrum Beta-Lactamase-Producing Enterobacterales Bloodstream Infections in Haematological Patients.Infectious diseases and therapy · 2022
Article
Epidemiology of ESBL-producing Escherichia coli from repeated prevalence studies over 11 years in a long-term-care facility.Antimicrobial resistance and infection control · 2021
Article
Prevalence of multidrug-resistant bacteria colonisation among asylum seekers in western Switzerland.Journal of infection prevention · 2021
Article
Multiple drug resistance bacterial isolates and associated factors among urinary stone patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.BMC urology · 2021
Article
Local prevalence of extended-spectrum beta-lactamase (ESBL) producingBMJ open · 2019
Article
Extended-spectrum β-lactamase-producing E. coli septicemia among rectal carriers in the ICU.Medicine · 2018
Observational
A prospective surveillance study for multidrug-resistant bacteria colonization in hospitalized patients at a Thai University Hospital.Antimicrobial resistance and infection control · 2018
Article
Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application.Drugs & aging · 2017
Review
Nosocomial Infections: Multicenter surveillance of antimicrobial resistance profile of Staphylococcus aureus and Gram negative rods isolated from blood and other sterile body fluids in Iran.Iranian journal of microbiology · 2015
Article
Antimicrobials increase travelers' risk of colonization by extended-spectrum betalactamase-producing Enterobacteriaceae.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Janet PasrichaInfection Control Program, University of Geneva Hospitals and Medical Faculty, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva 14, Switzerland ; The Jenner Institute, University of Oxford, Oxford, UK.

Thibaud KoesslerDepartment of General Internal Medicine, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.

Stephan HarbarthInfection Control Program, University of Geneva Hospitals and Medical Faculty, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva 14, Switzerland.

Jacques SchrenzelCentral Laboratory of Bacteriology, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.

Véronique CamusInfection Control Program, University of Geneva Hospitals and Medical Faculty, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva 14, Switzerland.

Gilles CohenDivision of Medico-Economic Analysis, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.

Arnaud PerrierDepartment of General Internal Medicine, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.

Didier PittetInfection Control Program, University of Geneva Hospitals and Medical Faculty, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva 14, Switzerland ; WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.

Anne ItenInfection Control Program, University of Geneva Hospitals and Medical Faculty, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva 14, Switzerland ; Department of General Internal Medicine, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of extended-spectrum beta-lactamase producing-enterobacteriacae (ESBL-E) infection is rising worldwide. We aimed to determine the prevalence and nosocomial acquisition rate of ESBL-E as well as the risk factors for ESBL-E carriage and acquisition amongst patients consecutively admitted to 13 internal medicine units at our hospital who were not previously known to be ESBL-E carriers.

findingsWe screened all patients admitted or transferred to internal medicine units for ESBL-E on admission and discharge using rectal swabs. Of 1072 patients screened, 51 (4.8%) were carriers of an ESBL-E at admission. Of 473 patients who underwent admission and discharge screening, 21 (4.4%) acquired an ESBL-E. On multivariate analysis, diabetes mellitus without end-organ complications (OR 2.87 [1.09-7.08]), connective tissue disease (OR 7.22 [1.17-44.59]), and liver failure (OR 8.39 [1.55-45.45]) were independent risk factors for carriage of an ESBL-E upon admission to hospital (area under the ROC curve, 0.68). Receipt of a first- or second-generation cephalosporin (OR 9.25 [2.22-37.82]), intra-hospital transfer (OR 6.68 [1.71-26.06]), and a hospital stay >21 days (OR 25.17 [4.18-151.68]) were associated with acquisition of an ESBL-E during hospitalisation; whilst admission from home was protective (OR 0.16 [0.06-0.39]) on univariate regression. No risk profile with sufficient accuracy to predict previously unknown carriage on admission or acquisition of ESBL-E could be developed using readily available patient information.

conclusionsESBL-E carriage is endemic amongst internal medicine patients at our institution. We were unable to develop a clinical risk profile to accurately predict ESBL-E carriage amongst these patients.

Indexed as

Antimicrobial resistanceExtended-spectrum beta-lactamase producing enterobacteraciaeInfection control

Identifiers

PMID23759067

DOI10.1186/2047-2994-2-20

PMCPMC3711782

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.