ArticleBMC neurology2013
Incidence of multiple sclerosis among European Economic Area populations, 1985-2009: the framework for monitoring.
Article in BMC neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Incidence and Prevalence of Multiple Sclerosis in Malmö, Southern Sweden.Multiple sclerosis international · 2022Article
- Genetic Alterations in Patients with Two Clinical Phenotypes of Multiple Sclerosis.Journal of molecular neuroscience : MN · 2020Article
- Pregnancy Outcomes in Patients With Multiple Sclerosis Exposed to Natalizumab-A Retrospective Analysis From the Austrian Multiple Sclerosis Treatment Registry.Frontiers in neurology · 2020Article
- Dietary Composition and Effects in Inflammatory Bowel Disease.Nutrients · 2019Review
- Hormonal contraception and the development of autoimmunity: A review of the literature.The Linacre quarterly · 2017Article
- Evaluation of pregnancy outcomes from the Tysabri® (natalizumab) pregnancy exposure registry: a global, observational, follow-up study.BMC neurology · 2016Observational
- Article
- Diet in the pathogenesis and treatment of inflammatory bowel diseases.Gastroenterology · 2015Review
- Incidence of multiple sclerosis in Northern Lisbon, Portugal: 1998-2007.BMC neurology · 2014Article
- Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature.Patient preference and adherence · 2014Review
- Responsiveness of the Multiple Sclerosis International Quality of Life questionnaire to disability change: a longitudinal study.Health and quality of life outcomes · 2013Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA debate surrounding multiple sclerosis epidemiology has centred on time-related incidence increases and the need of monitoring. The purpose of this study is to reassess multiple sclerosis incidence in the European Economic Area.
methodsWe conducted a systematic review of literature from 1965 onwards and integrated elements of original research, including requested or completed data by surveys authors and specific analyses.
resultsThe review of 5323 documents yielded ten studies for age- and sex-specific analyses, and 21 studies for time-trend analysis of single data sets. After 1985, the incidence of multiple sclerosis ranged from 1.12 to 6.96 per 100,000 population, was higher in females, tripled with latitude, and doubled with study midpoint year. The north registered increasing trends from the 1960s and 1970s, with a historic drop in the Faroe Islands, and fairly stable data in the period 1980-2000; incidence rose in Italian and French populations in the period 1970-2000, in Evros (Greece) in the 1980s, and in the French West Indies in around 2000.
conclusionsWe conclude that the increase in multiple sclerosis incidence is only apparent, and that it is not specific to women. Monitoring of multiple sclerosis incidence might be appropriate for the European Economic Area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.