ArticleBMC psychiatry2013
Neurocognitive function in bipolar disorder: a comparison between bipolar I and II disorder and matched controls.
Article in BMC psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Brain grey-matter volume alteration in adult patients with bipolar disorder under different conditions: a voxel-based meta-analysisJournal of psychiatry & neuroscience : JPN · 2019Pooled it
- [Schizophrenia and bipolar disorder : Treatment of cognitive impairments].Der Nervenarzt · 2018Pooled it
- Neurocognitive functioning in euthymic patients with bipolar disorder and unaffected relatives: A review of the literature.Neuroscience and biobehavioral reviews · 2016Pooled it
- Clinical prescription of lithium, anticonvulsants antipsychotics, and antidepressants for major mood disorders.International journal of bipolar disorders · 2025Article
- Factors Associated With Insight Toward Illness in Patients With Bipolar Disorder Type 1 in Manic Episodes.Alpha psychiatry · 2025Article
- The St. Göran Project: A Multipronged Strategy for Longitudinal Studies for Bipolar Disorders.Neuropsychobiology · 2025Article
- Cognitive functions in euthymic bipolar I and II patients: a cross sectional study.Frontiers in psychiatry · 2025Article
- Neurocognitive function across different phases of bipolar disorder: an evaluation using the B-CATS.Frontiers in psychiatry · 2025Article
- Cognitive attentional syndrome and metacognitive beliefs as potential treatment targets for metacognitive therapy in bipolar disorder.World journal of psychiatry · 2021Review
- Long-term trajectory of cognitive performance in people with bipolar disorder and controls: 6-year longitudinal study.BJPsych open · 2021Article
- Common and Specific Characteristics of Adolescent Bipolar Disorder Types I and II: A Combined Cortical Thickness and Structural Covariance Analysis.Frontiers in psychiatry · 2021Article
- Executive functioning but not IQ or illness severity predicts occupational status in bipolar disorder.International journal of bipolar disorders · 2020Article
- Predictors of Functional Outcome in Patients With Bipolar Disorder: Effects of Cognitive Psychoeducational Group Therapy After 12 Months.Frontiers in psychiatry · 2020Article
- Bipolar II Disorder Is a Myth.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2019Article
- Neuropsychological profiles of adult bipolar disorder patients with and without comorbid attention-deficit hyperactivity disorder.International journal of bipolar disorders · 2019Article
- Comparing Neurocognitive Profile of Patients with Borderline Personality and Bipolar-II Disorders.Iranian journal of psychiatry · 2019Article
- Inflammation, Glutamate, and Cognition in Bipolar Disorder Type II: A Proof of Concept Study.Frontiers in psychiatry · 2019Article
- Bipolar disorder type I and II show distinct relationships between cortical thickness and executive function.Acta psychiatrica Scandinavica · 2018Article
- Cerebrospinal fluid microglia and neurodegenerative markers in twins concordant and discordant for psychotic disorders.European archives of psychiatry and clinical neuroscience · 2017Article
- Deconstructing Bipolar Disorder and Schizophrenia: A cross-diagnostic cluster analysis of cognitive phenotypes.Journal of affective disorders · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCognitive deficits have been documented in patients with bipolar disorder. Further, it has been suggested that the degree and type of cognitive impairment differ between bipolar I and bipolar II disorder, but data is conflicting and remains inconclusive. This study aimed to clarify the suggested differences in cognitive impairment between patients with bipolar I and II disorder in a relatively large, clinically stable sample while controlling for potential confounders.
methods67 patients with bipolar I disorder, 43 with bipolar II disorder, and 86 randomly selected population-based healthy controls were compared. A number of neuropsychological tests were administered, assessing verbal and visual memory and executive functions. Patients were in a stable phase during testing.
resultsPatients with bipolar type I and type II were cognitively impaired compared to healthy controls, but there were no statistically significant differences between the two subtypes. The strongest predictor of cognitive impairment within the patient group was current antipsychotic treatment.
conclusionsThe present study suggests that the type and degree of cognitive dysfunction is similar in bipolar I and II patients. Notably, treatment with antipsychotics - but not a history of psychosis - was associated with more severe cognitive impairment. Given that patients with bipolar I disorder are more likely to be on antipsychotic drugs, this might explain why some previous studies have found that patients with type I bipolar disorder are more cognitively impaired than those with type II.
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