Evidence map›Paper›PMID 23758751›Full record

SynthesisInternational journal of paediatric dentistry2013

Dental caries prevalence in children and adolescents with cystic fibrosis: a qualitative systematic review and recommendations for future research.

Donald L Chi

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of paediatric dentistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Impact of rare diseases in oral health.Medicina oral, patologia oral y cirugia bucal · 2016
    Pooled it
  3. Association of dental diseases with pulmonary outcomes in a multicenter cohort of adolescents and young adults with CF.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2026
    Observational
  4. Oral health and related outcomes in children and adolescents with cystic fibrosis: a scoping review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Age-related heterogeneity in dental caries and associated risk factors in individuals with cystic fibrosis ages 6-20 years: A pilot study.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2018
    Observational
  9. Article
  10. Dental treatment for people with cystic fibrosis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2016
    Review
  11. Article
  12. Related factors of dental caries and molar incisor hypomineralisation in a group of children with cystic fibrosis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Donald L ChiDepartment of Oral Health Sciences, University of Washington, Seattle, WA 98195, USA. dchi@uw.edu
University of Washington · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss · 2010 to 2026
$21.4M
Addressing Oral Health Disparities in Medicaid-Enrolled Special Needs Children wiK08DE020856 · NIDCR · UNIVERSITY OF WASHINGTON · PI CHI, DONALD LESLIE · 2010 to 2014
$627k
NIDCR NIH HHS K08 DE020856NIDCR NIH HHS K08DE020856NIDDK NIH HHS P30 DK089507NIMHD NIH HHS L60 MD003921
6 · The paper itself

Abstract

backgroundChildren and adolescents with cystic fibrosis (CF) are believed to be at low risk for dental caries, but this paradigm has not been critically evaluated.

aimsTo conduct a qualitative systematic review of the international literature on dental caries prevalence in children and adolescents with CF and make recommendations on future CF-related oral health research priorities.

designThe Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement was used to identify relevant studies published between 1960 and 2013.

resultsThe search resulted in 696 studies. Fifteen publications were included in the qualitative systematic review. Ten studies concluded that children with CF had significantly lower caries prevalence than control children, three studies reported that children with CF had higher caries prevalence, and two studies found no difference by CF status. Of the seven studies including age-based subgroup analyses, only one study supported the current paradigm. All studies had limitations that may bias study results.

conclusionsWhile children with CF may be a lower risk for dental caries, adolescents with CF may not be at lower caries than those without CF. Additional research is needed to evaluate a potentially flawed paradigm regarding caries risk in children and adolescents with CF.

Indexed as

AdolescentChildCystic FibrosisDental CariesHumansPrevalence

Identifiers

PMID23758751
PMCPMC3745806
OpenAlexW2025928475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.