ArticleSomatosensory & motor research2013
Recovery of fine motor performance after ischemic damage to motor cortex is facilitated by cell therapy in the rhesus monkey.
Article in Somatosensory & motor research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 21 citations in OpenAlex.
- Long-term exploratory evaluation of an acellular biomimetic polyfascicular nerve guidance conduit for peripheral nerve repair in a rhesus macaque model.Bioactive materials · 2027Article
- Is there a correlation between functional recovery of manual dexterity after motor cortex lesion and initial motor learning slope in the intact state?Frontiers in systems neuroscience · 2026Article
- Re-Examination and Extension of Manual Dexterity Behavioral Data in M1 Lesioned Adult Macaque Monkeys: A Survey of Therapies Induced Enhancement of Functional Recovery.Neuroscience insights · 2026Article
- Multicompartment Quantitative Proteomics Revealing Potential Mechanisms Underlying the Treatment Effects of Mesenchymal-Derived Extracellular Vesicles in a Monkey Model of Cortical Injury.Journal of proteome research · 2025Article
- Birefringence microscopy enables rapid, label-free quantification of myelin debris following induced cortical injury.Neurophotonics · 2025Article
- Confirmation of the Enhancement Effect of ANCE Treatment on Functional Recovery of Manual Dexterity From Primary Motor Cortex (M1) Lesion in Adult Macaque Monkeys.Brain and behavior · 2025Article
- Reduction of inflammatory biomarkers underlies extracellular vesicle mediated functional recovery in an aged monkey model of cortical injury.Frontiers in aging neuroscience · 2025Article
- Sex differences in recovery of motor function in a rhesus monkey model of cortical injury.Biology of sex differences · 2021Article
- Extracellular vesicles derived from bone marrow mesenchymal stem cells enhance myelin maintenance after cortical injury in aged rhesus monkeys.Experimental neurology · 2021Article
- Quantitative birefringence microscopy for imaging the structural integrity of CNS myelin following circumscribed cortical injury in the rhesus monkey.Neurophotonics · 2021Article
- Impaired Hand Dexterity Function in a Non-human Primate Model with Chronic Parkinson's Disease.Experimental neurobiology · 2020Article
- Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke.Experimental neurobiology · 2020Article
- Cell based therapy reduces secondary damage and increases extent of microglial activation following cortical injury.Brain research · 2019Article
- A method for assessing recovery of fine motor function of the hand in a rhesus monkey model of cortical injury: an adaptation of the Fugl-Meyer Scale and Eshkol-Wachman Movement Notation.Somatosensory & motor research · 2019Article
- Mesenchymal derived exosomes enhance recovery of motor function in a monkey model of cortical injury.Restorative neurology and neuroscience · 2019Article
- Cell based therapy enhances activation of ventral premotor cortex to improve recovery following primary motor cortex injury.Experimental neurology · 2018Article
- Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Oral curcumin supplementation improves fine motor function in the middle-aged rhesus monkey.Somatosensory & motor research · 2018Article
- Sustained-releasing hollow microparticles with dual-anticancer drugs elicit greater shrinkage of tumor spheroids.Oncotarget · 2017Article
- Inosine enhances recovery of grasp following cortical injury to the primary motor cortex of the rhesus monkey.Restorative neurology and neuroscience · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
We investigated the efficacy on recovery of function following controlled cortical ischemia in the monkey of the investigational cell drug product, CNTO 0007. This drug contains a cellular component, human umbilical tissue-derived cells, in a proprietary thaw and inject formulation. Results demonstrate significantly better recovery of motor function in the treatment group with no difference between groups in the volume or surface area of ischemic damage, suggesting that the cells stimulated plasticity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.