Trial reportDiabetes care2013
Effect of intensive lifestyle intervention on sexual dysfunction in women with type 2 diabetes: results from an ancillary Look AHEAD study.
Trial report in Diabetes care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 75 citations in OpenAlex.
- Heterogeneity of Treatment Effects From an Intensive Lifestyle Weight Loss Intervention on Cardiovascular Events in Patients With Type 2 Diabetes: Data From the Look AHEAD Trial.Diabetes care · 2019Trial
- A lifestyle intervention improves sexual function of women with obesity and infertility: A 5 year follow-up of a RCT.PloS one · 2018Trial
- Implications of Look AHEAD for clinical trials and clinical practice.Diabetes, obesity & metabolism · 2014Trial
- Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study.Obesity (Silver Spring, Md.) · 2014Trial
- 4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Auto Machine Learning and Convolutional Neural Network in Diabetes Mellitus Research-The Role of Histopathological Images in Designing and Exploring Experimental Models.Biomedicines · 2025Article
- 4. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes-2025.Diabetes care · 2025Review
- Influence of Gender in Diabetes Mellitus and Its Complication.International journal of molecular sciences · 2022Review
- Proposal of an obesity classification based on weight history: an official document by the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Society for the Study of Obesity and Metabolic Syndrome (ABESO).Archives of endocrinology and metabolism · 2022Article
- Barocrinology: The Endocrinology of Obesity from Bench to Bedside.Medical sciences (Basel, Switzerland) · 2020Review
- Does sexual functioning improve with migraine improvements and/or weight loss?-A post hoc analysis in the Women's Health and Migraine (WHAM) trial.Obesity science & practice · 2020Article
- Male and female sexual dysfunction in diabetic subjects: Focus on new antihyperglycemic drugs.Reviews in endocrine & metabolic disorders · 2020Review
- Effect of Body Weight on Sexual Function in Men and Women.Current sexual health reports · 2019Article
- Metabolic and Endocrine Consequences of Bariatric Surgery.Frontiers in endocrinology · 2019Review
- From inflammation to sexual dysfunctions: a journey through diabetes, obesity, and metabolic syndrome.Journal of endocrinological investigation · 2018Review
- Treatment of Obesity in Patients With Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2017Article
- Relationships of Sexual Dysfunction with Depression and Acceptance of Illness in Women and Men with Type 2 Diabetes Mellitus.International journal of environmental research and public health · 2017Article
- Weight Loss and Improvement in Comorbidity: Differences at 5%, 10%, 15%, and Over.Current obesity reports · 2017Review
- Sexual Dysfunction in Women With Migraine and Overweight/Obesity: Relative Frequency and Association With Migraine Severity.Headache · 2017Article
- Sexual function in multiple sclerosis and associations with demographic, disease and lifestyle characteristics: an international cross-sectional study.BMC neurology · 2016Article
Corrections and comments
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Authors and funding
12 authors at 11 institutions in 1 country.
Funding
Abstract
objectiveSexual dysfunction is a prevalent problem in obese women with type 2 diabetes. This study examined the effects of intensive lifestyle intervention (ILI) in these women. RESEARCH DESIGN AND
methodsLook AHEAD is a 16-center, randomized, controlled trial evaluating the health effects of ILI compared with a control group (diabetes support and education [DSE]). The Look AHEAD Sexual Function Ancillary study included 375 female participants at five Look AHEAD sites. Participants completed the Female Sexual Function Inventory (FSFI) and Beck Depression Inventory (BDI), and assessments of weight and cardiovascular risk factors at baseline and 1 year were made.
resultsAt baseline, 50% of the 229 participants who reported being sexually active met criteria for female sexual dysfunction (FSD); only BDI score was related to FSD. One-year weight losses were greater in the ILI group than in the DSE group (7.6 vs. 0.45 kg; P<0.001). Among women with FSD at baseline, those in the ILI group (N=60) compared with those in the DSE group (N=53) were significantly more likely to remain sexually active (83 vs. 64%; P<0.008), reported greater improvement in total FSFI scores and in most FSFI domains (P<0.05), and were more likely to experience remission of FSD (28 vs. 11%; P<0.04) at 1 year. No significant differences between ILI and DSE were seen in women who did not have FSD at baseline.
conclusionsParticipation in ILI appeared to have beneficial effects on sexual functioning among obese women with diabetes, particularly in those who had FSD at baseline.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.