Evidence map›Paper›PMID 23756717›Full record

Trial reportChild psychiatry and human development2014

Prospective relationship between obsessive-compulsive and depressive symptoms during multimodal treatment in pediatric obsessive-compulsive disorder.

Johanna M Meyer, Joseph P H McNamara, Adam M Reid, Eric A Storch, Gary R Geffken, Dana M Mason, Tanya K Murphy, Regina Bussing

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Child psychiatry and human development, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Quality of Life in Children and Youth with Obsessive-Compulsive Disorder.Journal of child and adolescent psychopharmacology · 2018
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Residential treatment outcomes for adolescents with obsessive-compulsive disorder.Psychotherapy research : journal of the Society for Psychotherapy Research · 2016
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Johanna M MeyerDivision of Medical Psychology, Department of Psychiatry, University of Florida, P.O. Box 100234, 1600 S Archer Rd, Gainesville, FL, 32611, USA, jmmeyer@ufl.edu.
Joseph P H McNamara
Adam M Reid
Eric A Storch
Gary R Geffken
Dana M Mason
Tanya K Murphy
Regina Bussing
University of Florida · USUniversity of Florida Health · USUniversity of South Florida · US

Funding

SSRI-Induced Activation Syndrome In Pediatric OCDU01MH078594 · NIMH · UNIVERSITY OF FLORIDA · PI BUSSING, REGINA · 2007 to 2010
$928k
NIMH NIH HHS U01 MH078594
6 · The paper itself

Abstract

The present study examined the prospective relationship between obsessive-compulsive and depressive symptoms during a multimodal treatment study involving youth with obsessive-compulsive disorder (OCD). Participants included fifty-six youth, aged 7-17 years (M = 12.16 years) who were enrolled in a two-site randomized controlled pharmacological and cognitive behavioral therapy treatment trial. Obsessive-compulsive severity was measured using the Children's Yale-Brown Obsessive-Compulsive Scale, and depressive symptoms were rated using the Children's Depression Rating Scale-Revised. Multi-level modeling analyses indicated that, on average over the course of treatment, variable and less severe obsessive-compulsive symptoms significantly predicted a decrease in depressive symptoms. Additionally, week-to-week fluctuations in OCD severity did not significantly predict weekly changes in depressive symptom severity. Level of baseline depressive symptom severity did not moderate these relationships. Findings suggest that when treating youth with OCD with co-occurring depression, therapists should begin by treating obsessive-compulsive symptoms, as when these are targeted effectively, depressive symptoms diminish as well.

Indexed as

AdolescentChildCognitive Behavioral TherapyCombined Modality TherapyCompulsive BehaviorDepressionFemaleHumansMaleObsessive BehaviorObsessive-Compulsive DisorderSelective Serotonin Reuptake InhibitorsSertralineSeverity of Illness IndexSymptom AssessmentSelective Serotonin Reuptake InhibitorsSertraline

Identifiers

PMID23756717
OpenAlexW1997816679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.