Evidence map›Paper›PMID 23756381›Full record

ArticleNature communications2013

Integrating DNA strand-displacement circuitry with DNA tile self-assembly.

David Yu Zhang, Rizal F Hariadi, Harry M T Choi, Erik Winfree

Abstract read
In one paragraph

Article in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Dynamic control of DNA condensation.Nature communications · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Orthogonal Enzyme-Driven Timers for DNA Strand Displacement Reactions.Journal of the American Chemical Society · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David Yu ZhangDepartment of Computation and Neural Systems, California Institute of Technology, Pasadena, California, USA. dyz1@rice.edu
Rizal F Hariadi
Harry M T Choi
Erik Winfree

Funding

Bio-imaging with Isothermal DNA Self-AssemblyR00EB015331 · NIBIB · RICE UNIVERSITY · PI ZHANG, DAVID YU · 2013 to 2015
$735k
Bio-imaging with Isothermal DNA Self-AssemblyK99EB015331 · NIBIB · HARVARD MEDICAL SCHOOL · PI ZHANG, DAVID YU · 2012 to 2013
$179k
Howard Hughes Medical InstituteNIBIB NIH HHS 1K99EB015331NIBIB NIH HHS K99 EB015331NIBIB NIH HHS R00 EB015331
6 · The paper itself

Abstract

DNA nanotechnology has emerged as a reliable and programmable way of controlling matter at the nanoscale through the specificity of Watson-Crick base pairing, allowing both complex self-assembled structures with nanometer precision and complex reaction networks implementing digital and analog behaviors. Here we show how two well-developed frameworks, DNA tile self-assembly and DNA strand-displacement circuits, can be systematically integrated to provide programmable kinetic control of self-assembly. We demonstrate the triggered and catalytic isothermal self-assembly of DNA nanotubes over 10 μm long from precursor DNA double-crossover tiles activated by an upstream DNA catalyst network. Integrating more sophisticated control circuits and tile systems could enable precise spatial and temporal organization of dynamic molecular structures.

Indexed as

CatalysisDNAKineticsMicroscopy, FluorescenceNanotechnologyNanotubesTime-Lapse ImagingDNA

Identifiers

PMID23756381
PMCPMC3709499

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.