Evidence map›Paper›PMID 23756050›Full record

ReviewCurrent opinion in microbiology2013

Striking a balance: fungal commensalism versus pathogenesis.

Iliyan D Iliev, David M Underhill

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Article
  3. Discovering a new paradigm: Gut microbiota as a central modulator of sexual health.World journal of gastrointestinal pathophysiology · 2025
    Review
  4. Review
  5. Gut Microbiota of Ruminants and Monogastric Livestock: An Overview.Animals : an open access journal from MDPI · 2025
    Review
  6. Advancements in vaginal microbiota,Microbial cell (Graz, Austria) · 2025
    Review
  7. Frontiers in parasitology · 2025
    Article
  8. New insights in the role ofFrontiers in microbiology · 2025
    Article
  9. ThemBio · 2024
    Article
  10. Article
  11. Retracing the evolution ofMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. [Characteristics and research progress on the role of intestinal fungi in chronic liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  18. Review
  19. Lycorine Alkaloid andMolecules (Basel, Switzerland) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Iliyan D IlievF. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Iliyan.Iliev@cshs.org
David M Underhill

Funding

Host immunity to commensal gut fungiR01DK093426 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI UNDERHILL, DAVID M. · 2012 to 2021
$3.7M
NIDDK NIH HHS R01 DK093426
6 · The paper itself

Abstract

The environment is suffused with nearly countless types of fungi, and our immune systems must be tuned to cope with constant exposure to them. In addition, it is becoming increasingly clear that many surfaces of our bodies are colonized with complex populations of fungi (the mycobiome) in the same way that they are colonized with complex populations of bacteria. The immune system must tolerate colonization with commensal fungi but defend against fungal invasion. Truly life-threatening fungal infections are common only when this balance is disrupted through, for example, profound immunosuppression or genetic mutation. Recent studies have begun to shed light on how this balance is established and maintained, and suggest future studies on the role of fungi in homeostatic conditions.

Indexed as

SymbiosisAnimalsFungiHumansVirulence

Identifiers

PMID23756050
PMCPMC3742553

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.