ArticleF1000prime reports2013
Metabolic phenotyping and systems biology approaches to understanding neurological disorders.
Article in F1000prime reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Metabolic fingerprint of progression of chronic hepatitis B: changes in the metabolome and novel diagnostic possibilities.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Metabolomics in Central Sensitivity Syndromes.Metabolites · 2020Review
- ASIC3-dependent metabolomics profiling of serum and urine in a mouse model of fibromyalgia.Scientific reports · 2019Article
- Diet-induced metabolic changes of the human gut microbiome: importance of short-chain fatty acids, methylamines and indoles.Acta diabetologica · 2019Review
- Genetic and biochemical changes of the serotonergic system in migraine pathobiology.The journal of headache and pain · 2017Review
- A diagnostic biomarker profile for fibromyalgia syndrome based on an NMR metabolomics study of selected patients and controls.BMC neurology · 2017Article
- Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers.Frontiers in molecular neuroscience · 2016Article
- An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data.Metabolomics : Official journal of the Metabolomic Society · 2015Article
- Brain region mapping using global metabolomics.Chemistry & biology · 2014Article
- Cerebrospinal fluid analysis in Alzheimer's disease: technical issues and future developments.Journal of neurology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of high-throughput metabolic profiling and the study of the metabolome are particularly important in brain research where small molecules or metabolites play fundamental signalling roles: neurotransmitters, signalling lipids, osmolytes and even ions. Metabolic profiling has shown that metabolic perturbations in the brain go beyond alterations of neurotransmission and that variations in brain metabolic homeostasis are associated with neurological disorders. In this report, we will focus on recent developments in the field of metabolic phenotyping that have contributed to unravelling the pathophysiology of neurological diseases. Also, we will highlight the necessity of implementing systems biology approaches to integrate metabolic data and tackle the structural and functional complexity of the brain in normal and pathological conditions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.