Evidence map›Paper›PMID 23755180›Full record

ArticlePloS one2014

Socioeconomic status, functional recovery, and long-term mortality among patients surviving acute myocardial infarction.

David A Alter, Barry Franklin, Dennis T Ko, Peter C Austin, Douglas S Lee, Paul I Oh, Therese A Stukel, Jack V Tu

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Guideline
  2. The Diagnosis of Chronic Coronary Heart Disease.Deutsches Arzteblatt international · 2017
    Pooled it
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  11. The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

David A AlterThe Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada. david.alter@ices.on.ca
Barry Franklin
Dennis T Ko
Peter C Austin
Douglas S Lee
Paul I Oh
Therese A Stukel
Jack V Tu
Institute for Clinical Evaluative Sciences · CABeaumont Hospital, Royal Oak · USToronto Rehabilitation Institute · CA

Funding

Canadian Institutes of Health Research MOP#119956
6 · The paper itself

Abstract

objectivesTo examine the relationship between socio-economic status (SES), functional recovery and long-term mortality following acute myocardial infarction (AMI).

backgroundThe extent to which SES mortality disparities are explained by differences in functional recovery following AMI is unclear.

methodsWe prospectively examined 1368 patients who survived at least one-year following an index AMI between 1999 and 2003 in Ontario, Canada. Each patient was linked to administrative data and followed over 9.6 years to track mortality. All patients underwent medical chart abstraction and telephone interviews following AMI to identify individual-level SES, clinical factors, processes of care (i.e., use of, and adherence, to evidence-based medications, physician visits, invasive cardiac procedures, referrals to cardiac rehabilitation), as well as changes in psychosocial stressors, quality of life, and self-reported functional capacity.

resultsAs compared with their lower SES counterparts, higher SES patients experienced greater functional recovery (1.80 ml/kg/min average increase in peak V02, P<0.001) after adjusting for all baseline clinical factors. Post-AMI functional recovery was the strongest modifiable predictor of long-term mortality (Adjusted HR for each ml/kg/min increase in functional capacity: 0.91; 95% CI: 0.87-0.94, P<0.001) irrespective of SES (P = 0.51 for interaction between SES, functional recovery, and mortality). SES-mortality associations were attenuated by 27% after adjustments for functional recovery, rendering the residual SES-mortality association no longer statistically significant (Adjusted HR: 0.84; 95% CI:0.70-1.00, P = 0.05). The effects of functional recovery on SES-mortality associations were not explained by access inequities to physician specialists or cardiac rehabilitation.

conclusionsFunctional recovery may play an important role in explaining SES-mortality gradients following AMI.

Indexed as

Recovery of FunctionAgedDelivery of Health CareDepressionFemaleHumansIncomeMaleMiddle AgedMyocardial InfarctionOntarioSecondary PreventionStress, PsychologicalSurvival AnalysisTime Factors

Identifiers

PMID23755180
PMCPMC3670842
OpenAlexW2050101071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.