ArticlePloS one2014
The clinical characteristics, carbapenem resistance, and outcome of Acinetobacter bacteremia according to genospecies.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Appropriate initial antibiotic therapy in hospitalized patients with gram-negative infections: systematic review and meta-analysis.BMC infectious diseases · 2015Pooled it
- Clinical Implications of Bacteremia Caused by Non-Biomedicines · 2025Article
- The global epidemiology of carbapenem-resistantJAC-antimicrobial resistance · 2025Review
- Characterization of the Diversity in Host Range of an Extensively Drug-Resistant (XDR) Type IV Secretion System-Encoding Plasmid inPathogens (Basel, Switzerland) · 2025Article
- Molecular epidemiology of Acinetobacter baumannii complex causing invasive infections in Korean children during 2001-2020.Annals of clinical microbiology and antimicrobials · 2023Article
- Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.AMB Express · 2022Article
- Genetic Resistance Determinants in ClinicalAntibiotics (Basel, Switzerland) · 2022Article
- A Variant Carbapenem Inactivation Method (CIM) forPathogens (Basel, Switzerland) · 2022Article
- Colistin-ResistantMicroorganisms · 2020Article
- Chromosome Architecture and Gene Content of the Emergent PathogenFrontiers in microbiology · 2020Article
- Antimicrobial susceptibility pattern ofThe Pan African medical journal · 2019Article
- Article
- Acinetobacter spp. are associated with a higher mortality in intensive care patients with bacteremia: a survival analysis.BMC infectious diseases · 2016Article
- Identification of Acinetobacter Species Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry.Annals of laboratory medicine · 2016Article
- Outer membrane Protein A plays a role in pathogenesis of Acinetobacter nosocomialis.Virulence · 2016Article
- Utility of Whole-Genome Sequencing in Characterizing Acinetobacter Epidemiology and Analyzing Hospital Outbreaks.Journal of clinical microbiology · 2016Article
- Influence of ACB complex genospecies on clinical outcomes in a U.S. hospital with high rates of multidrug resistance.The Journal of infection · 2015Article
- Update on the Epidemiology, Treatment, and Outcomes of Carbapenem-resistant Acinetobacter infections.Chonnam medical journal · 2014Review
- Clinical outcomes of hospital-acquired infection with Acinetobacter nosocomialis and Acinetobacter pittii.Antimicrobial agents and chemotherapy · 2014Article
- Identification, genotypic relation, and clinical features of colistin-resistant isolates of Acinetobacter genomic species 13BJ/14TU from bloodstreams of patients in a university hospital.Journal of clinical microbiology · 2014Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew clinical data are available on the relationship between genospecies and outcome of Acinetobacter bacteremia, and the results are inconsistent. We performed this study to evaluate the relationship between genospecies and the outcome of Acinetobacter bacteremia.
methodsClinical data from 180 patients who had Acinetobacter bacteremia from 2003 to 2010 were reviewed retrospectively. The genospecies were identified by rpoB gene sequence analysis. The clinical features and outcomes of 90 patients with A. baumannii bacteremia were compared to those of 90 patients with non-baumannii Acinetobacter bacteremia (60 with A. nosocomialis, 17 with Acinetobacter species "close to 13 TU", 11 with A. pittii, and two with A. calcoaceticus).
resultsA. baumannii bacteremia was associated with intensive care unit-onset, mechanical ventilation, pneumonia, carbapenem resistance, and higher APACHE II scores, compared to non-baumannii Acinetobacter bacteremia (P<0.05). In univariate analyses, age, pneumonia, multidrug resistance, carbapenem resistance, inappropriate empirical antibiotics, higher APACHE II scores, and A. baumannii genospecies were risk factors for mortality (P<0.05). Multivariate analysis revealed A. baumannii genospecies (OR, 3.60; 95% CI, 1.56-8.33), age, pneumonia, and higher APACHE II scores to be independent risk factors for mortality (P<0.05).
conclusionA. baumannii genospecies was an independent risk factor for mortality in patients with Acinetobacter bacteremia. Our results emphasize the importance of correct species identification of Acinetobacter blood isolates.
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