ArticlePloS one2014
Transcriptomic analysis of cadmium stress response in the heavy metal hyperaccumulator Sedum alfredii Hance.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Plant Responses to Heavy Metal Stress: Molecular Mechanisms, Transcriptomic Regulation, and Multi-Omics Integration in Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Silicon and iron co-application modulates cadmium accumulation and cell wall composition in tomato seedlings.BMC plant biology · 2025Article
- Transcriptome and Physiological Analysis Reveals the Mechanism of Abscisic Acid in Regulating Cadmium Uptake and Accumulation in the HyperaccumulatorPlants (Basel, Switzerland) · 2025Article
- Lead-induced changes in plant cell ultrastructure: an overview.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Review
- Multiomics and biotechnologies for understanding and influencing cadmium accumulation and stress response in plants.Plant biotechnology journal · 2024Review
- Comparative transcriptome analysis between two different cadmium-accumulating genotypes of soybean (Glycine max) in response to cadmium stress.BMC genomic data · 2024Article
- Identification and expression analysis of expansin gene family in Salvia miltiorrhiza.Chinese medicine · 2024Article
- Exploring cadmium stress responses in sisal roots: Insights from biochemical and transcriptome analysis.PloS one · 2023Article
- Comparative transcriptomic analysis provides key genetic resources in clove basil (Frontiers in genetics · 2023Article
- Proteomic Changes inPlants (Basel, Switzerland) · 2022Article
- Comparative Analysis of Italian Lettuce (Genes · 2022Article
- Comparative Transcriptomics Analysis of Roots and Leaves under Cd Stress inInternational journal of molecular sciences · 2022Article
- Cadmium Exposure Alters Rhizospheric Microbial Community and Transcriptional Expression of Vetiver Grass.Frontiers in plant science · 2022Article
- Metabolome and transcriptome association analysis revealed key factors involved in melatonin mediated cadmium-stress tolerance in cotton.Frontiers in plant science · 2022Article
- Transcriptomic Analysis of Cadmium StressedFrontiers in plant science · 2022Article
- A Novel NCSTN Mutation in a Three-Generation Chinese Family with Hidradenitis Suppurative.Journal of healthcare engineering · 2022Article
- Comparative understanding of metal hyperaccumulation in plants: a mini-review.Environmental geochemistry and health · 2021Review
- Article
- Exogenous abscisic acid (ABA) promotes cadmium (Cd) accumulation in Sedum alfredii Hance by regulating the expression of Cd stress response genes.Environmental science and pollution research international · 2020Article
- Identification of Durum Wheat Cultivars and Their Tetraploid Relatives with Low Cadmium Content.Food technology and biotechnology · 2020Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Sedum alfredii Hance hyperaccumulating ecotype (HE) has the ability to hyperaccumulate cadmium (Cd), as well as zinc (Zn) and lead (Pb) in above-ground tissues. Although many physiological studies have been conducted with these plants, the molecular mechanisms underlying their hyper-tolerance to heavy metals are largely unknown. Here we report on the generation of 9.4 gigabases of adaptor-trimmed raw sequences and the assembly of 57,162 transcript contigs in S. alfredii Hance (HE) shoots by the combination of Roche 454 and Illumina/Solexa deep sequencing technologies. We also have functionally annotated the transcriptome and analyzed the transcriptome changes upon Cd hyperaccumulation in S. alfredii Hance (HE) shoots. There are 110 contigs and 123 contigs that were up-regulated (Fold Change ≥ 2.0) and down-regulated (Fold Change </=0.5) by chronic Cd treatment in S. alfredii Hance (HE) at q-value cutoff of 0.005, respectively. Quantitative RT-PCR was employed to compare gene expression patterns between S. alfredii Hance (HE) and non-hyperaccumulating ecotype (NHE). Our results demonstrated that several genes involved in cell wall modification, metal translocation and remobilization were more induced or constitutively expressed at higher levels in HE shoots than that in NHE shoots in response to Cd exposure. Together, our study provides large-scale expressed sequence information and genome-wide transcriptome profiling of Cd responses in S. alfredii Hance (HE) shoots.
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