ArticleFrontiers in psychology2013
Subthreshold Depressive Symptoms have a Negative Impact on Cognitive Functioning in Middle-Aged and Older Males.
Article in Frontiers in psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 33 citations in OpenAlex.
- Sex influences whether hippocampal volumes mediate the relationship between depression and cognition in older adults without dementia: A UK Biobank study.Brain imaging and behavior · 2025Article
- Functional activity level reported by an informant is an early predictor of Alzheimer's disease.BMC geriatrics · 2023Article
- Working memory updating in individuals with bipolar and unipolar depression: fMRI study.Translational psychiatry · 2022Article
- Predicting conversion to Alzheimer's disease in individuals with Mild Cognitive Impairment using clinically transferable features.Scientific reports · 2022Article
- Long-Lasting Cognitive Abnormalities after COVID-19.Brain sciences · 2021Article
- Memory Decline and Depression Onset in U.S. and European Older Adults.Journal of aging and health · 2020Article
- The Independent and Interactive Associations of Bilingualism and Sex on Cognitive Performance in Hispanics/Latinos of the Hispanic Community Health Study/Study of Latinos.Journal of Alzheimer's disease : JAD · 2019Article
- Vital Exhaustion and Incidence of Dementia: Results from the Copenhagen City Heart Study.Journal of Alzheimer's disease : JAD · 2019Article
- Mechanisms underlying the neuroprotective effect of brain reserve against late life depression.Journal of neural transmission (Vienna, Austria : 1996) · 2015Review
- Impact of age-related neuroglial cell responses on hippocampal deterioration.Frontiers in aging neuroscience · 2015Review
- Subclinical cognitive decline in middle-age is associated with reduced task-induced deactivation of the brain's default mode network.Human brain mapping · 2014Article
- Correlates of Subjective and Mild Cognitive Impairment: Depressive Symptoms and CSF Biomarkers.Dementia and geriatric cognitive disorders extra · 2013Article
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Authors and funding
3 authors at 2 institutions in 1 country.
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Abstract
introductionCognitive aging is associated with a decline on measures of fluid intelligence (gF), whereas crystallized intelligence (gC) tends to remain stable. In the present study we asked if depressive symptoms might contribute to explain the decline on gF in a sample of healthy middle-aged and older adults.
methodThe Norwegian sample included 83 females and 42 males (M = 60, SD = 7.9 years). gF was calculated from factor-analysis, including tests of matrix reasoning (WASI), memory function (CVLT-II), processing speed and executive function (CDT; CWIT). gC was derived from a Vocabulary subtest (WASI). Depressive symptoms were assessed by self-reports on Beck's Depression Index (BDI) and ranged from 0 to 21 (M = 6, SD = 4.5).
resultsIncreased age was correlated with a decline on gF (r = -0.436, p < 0.001), but not gC (r=-0.103, p = ns.). The BDI score in the whole sample was correlated with gF (r = -0.313, p < 0.001). A more detailed analysis showed that the BDI score correlated with measures of both gF and gC in males. The correlations were non-significant for females on all measures, with the exception of a measure of processing speed/executive function. A regression analysis including age and sex in the first step, showed that symptoms of depression significantly contributed to explain decline on gF, F(3, 124) = 16.653, p < 0.001, R? = 0.292, ΔR? = 0.054. DISCUSSION: The results showed that symptoms of depression were negatively correlated with cognitive functioning in males even when the symptom-level was below clinical threshold. This indicates that minimal symptoms of depression in older men are clinically relevant to address.
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