ArticleDevelopmental psychobiology2014
Age and sex differences in reward behavior in adolescent and adult rats.
Article in Developmental psychobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed.
- Latent variables for region of interest activation during the monetary incentive delay task.NeuroImage · 2021Trial
- Female rats are more vulnerable to binge drinking behavior in an operant self-administration paradigm: implication for transition to alcohol use disorders.Biology of sex differences · 2026Article
- Biomolecular correlates of incubated sucrose-seeking within ventromedial prefrontal cortex are sex- and subregion-selective.Pharmacology, biochemistry, and behavior · 2025Article
- Adolescent and adult age differences in palatable food learning and consumption.Physiology & behavior · 2025Article
- Impact of satiety on palatable food associative learning and consumption in male and female adult rats.Physiology & behavior · 2025Article
- Fractionating impulsivity and reward-related phenotypes in adolescent mice.Behavioural brain research · 2025Article
- Behavioral microanalyses refine sign-tracking characterization and uncover different response dynamics during omission and extinction learning.Learning & memory (Cold Spring Harbor, N.Y.) · 2025Article
- Sex-associated differences in incentive salience and drinking behaviour in a rodent model of alcohol relapse.Addiction biology · 2025Article
- Article
- Using sign tracking to experimentally increase self-control in rats.Journal of the experimental analysis of behavior · 2024Article
- Resting-state brain activation patterns and network topology distinguish human sign and goal trackers.Translational psychiatry · 2024Article
- Divergent reward cue representations in prefrontal cortex underlie differences in reward motivation between adolescents and adults.bioRxiv : the preprint server for biology · 2024Article
- Dorsomedial Striatum CB1R signaling is required for Pavlovian outcome devaluation in male Long Evans rats and reduces inhibitory synaptic transmission in both sexes.bioRxiv : the preprint server for biology · 2024Article
- Article
- Adolescents rats engage the orbitofrontal-striatal pathway differently than adults during impulsive actions.Scientific reports · 2024Article
- Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice.Journal of visualized experiments : JoVE · 2024Article
- The last stage of development: The restructuring and plasticity of the cortex during adolescence especially at puberty.Developmental psychobiology · 2024Article
- Chronic Methylphenidate Effects on Brain Gene Expression: An Exploratory Review.Psychology research and behavior management · 2024Review
- The role of sex on sign-tracking acquisition and outcome devaluation sensitivity in Long Evans rats.Behavioural brain research · 2023Article
- Observing a trained demonstrator influences associative appetitive learning in rats.Royal Society open science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Compared to adults, adolescents are at heightened risk for drug abuse and dependence. One of the factors contributing to this vulnerability may be age-dependent differences in reward processing, with adolescents approaching reward through stimulus-directed, rather than goal-directed, processes. However, the empirical evidence for this in rodent models of adolescence, particularly those that investigate both sexes, is limited. To address this, male and female rats that were adolescents (P30) or adults (P98) at the start of the experiment were trained in a Pavlovian approach (PA) task and were subsequently tested for the effects of reward devaluation, extinction, and re-acquisition. We found significant interactions between age and sex: females had enhanced acquisition of PA and poorer extinction, relative to males, while adolescents and females were less sensitive to reward devaluation than male adults. These results suggest that females and adolescents exhibit reward behavior that is more stimulus-directed, rather than goal-directed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.