ReviewUpdates in surgery2013
A review on functional results of sphincter-saving surgery for rectal cancer: the anterior resection syndrome.
Review in Updates in surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Effectiveness of nurse-led dietary modification recommendations in the management of defecation dysfunction among patients with rectal cancer after sphincter-saving surgery: a scoping review.Frontiers in surgery · 2026Pooled it
- The efficacy of retrograde and antegrade enemas in the management of low anterior resection syndrome in patients undergoing rectal resection: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Conversations for providers caring for patients with rectal cancer: Comparison of long-term patient-centered outcomes for patients with low rectal cancer facing ostomy or sphincter-sparing surgery.CA: a cancer journal for clinicians · 2016Pooled it
- Superior anal function in patients undergoing stoma closure within 6 months after LAR and analysis of factors associated with LARS syndrome: insights from experienced surgeons.Updates in surgery · 2025Review
- Article
- Laparoscopic versus open surgery for rectal neuroendocrine tumors: a multicenter real-world study.BMC cancer · 2024Article
- Article
- Shared Decision-Making, Sphincter Preservation, and Rectal Cancer Treatment: Identifying and Executing What Matters Most to Patients.Clinics in colon and rectal surgery · 2024Review
- Pelvic Floor Rehabilitation After Rectal Cancer Surgery One-year follow-up of a Multicenter Randomized Clinical Trial (FORCE trial).Annals of surgery · 2024Article
- Validity assessment of the POLARS score tool in the prediction of post rectal cancer surgery LARS score in a population-based Swedish cohort.BMJ open gastroenterology · 2024Article
- Article
- Preventive strategies for low anterior resection syndrome: a protocol for systematic review and evidence mapping.BMJ open · 2023Article
- Pelvic floor muscle exercises alleviate symptoms and improve mental health and rectal function in patients with low anterior resection syndrome.Frontiers in oncology · 2023Article
- Impact of defecation dysfunction on quality of life in mid-low rectal cancer patients following sphincter-sparing surgery.Asia-Pacific journal of oncology nursing · 2022Article
- MRI measurements predict major low anterior resection syndrome in rectal cancer patients.International journal of colorectal disease · 2022Article
- The role of colonic motility in low anterior resection syndrome.Frontiers in oncology · 2022Review
- A study on the clinical application of greater omental pedicle flap transplantation to correct anterior resection syndrome in patients with low rectal cancer.Regenerative therapy · 2021Article
- Analysis of presacral tissue structure in LARS and the prevention of LARS by reconstruction of presacral mesorectum with pedicled greater omentum flap graft.Techniques in coloproctology · 2021Article
- [Low anterior resection syndrome-Causes and treatment approaches].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Factors influencing anterior/low anterior resection syndrome after rectal or sigmoid resectionsTurkish journal of medical sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this review is to characterize the functional results and "anterior resection syndrome" (ARS) after sphincter-saving surgery for rectal cancer. The purpose of sphincter-saving operations is to save the anal sphincters by avoiding the need for rectal abdomino-perineal resection with a permanent stoma. A variety of alternative techniques have been proposed and, today, ultra-low anterior resections of the rectum are commonplace. Inevitably rectal resections modify anorectal physiology. The backdrop of the functional asset for ultralow anterior resections is related to a small neorectal capacity with high endo-neorectal pressures that act together on a weakened sphincteric mechanism. Sometimes a defecation disorder called ARS may be induced and the patient experiences an extremely low quality of life. Impaired bowel function is usually provoked either by colonic dysmotility, neorectal reservoir dysfunction, anal sphincter damage or by a combination of these factors. Surgical technique defects can contribute to these possible causes: anastomotic ischemia, short length of the descending colon and stretching of neorectal mesentery may play a role. Unfortunately, there is no therapeutic algorithm or gold standard treatment that may be used for ARS. Nevertheless, it is rational to use conservative therapy first and then resort to surgery. Drugs, rehabilitative treatment and sacral neuromodulation may be used; after failure of conservative methods, surgical treatment can be considered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.