ArticleWorld journal of surgery2013
Extended lymphadenectomy in colon cancer is crucial.
Article in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Brazilian Society of Surgical Oncology: Guidelines for the Lymphadenectomy in Colorectal Cancer.Journal of surgical oncology · 2025Guideline
- High Versus Low Ligation of the Inferior Mesenteric Artery in Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Laparoscopic versus open total mesorectal excision for rectal cancer.The Cochrane database of systematic reviews · 2014Pooled it
- D3 lymph node dissection in right-sided colon cancer: routine requirement or selective application?Journal of gastrointestinal oncology · 2025Article
- Efficacy of lymph node dissection around the inferior mesenteric artery with preservation of the left colic artery for rectal cancer.Annals of gastroenterological surgery · 2025Article
- Lymph node harvesting after laparoscopic complete mesocolic excision colectomy in colon cancer with practical application of glacial acid, absolute ethanol, water, and formaldehyde solution: A prospective cohort study.SAGE open medicine · 2024Article
- International survey among surgeons on the perioperative management of rectal cancer.Surgical endoscopy · 2023Article
- A propensity score-matched analysis of advanced energy devices and conventional monopolar device for colorectal cancer surgery: comparison of clinical and oncologic outcomes.Annals of surgical treatment and research · 2022Article
- Reconstructing topography and extent of injury to the superior mesenteric artery plexus in right colectomy with extended D3 mesenterectomy: a composite multimodal 3-dimensional analysis.Surgical endoscopy · 2022Article
- The significance of anatomical variation of the inferior mesenteric artery and its branches for laparoscopic radical resection of colorectal cancer: a review.World journal of surgical oncology · 2022Review
- Extended Lymphadenectomy for Proximal Transverse Colon Cancer: Is There a Place for Standardization?Medicina (Kaunas, Lithuania) · 2022Article
- Re-interpreting mesenteric vascular anatomy on 3D virtual and/or physical models: positioning the middle colic artery bifurcation and its relevance to surgeons operating colon cancer.Surgical endoscopy · 2022Article
- Short- and long-term outcomes of rectal cancer patients with high or improved low ligation of the inferior mesenteric artery.Scientific reports · 2020Article
- Article
- Complete mesocolic excision for colon cancer: is it worth it?Journal of gastrointestinal oncology · 2019Review
- Protocol for a multicentre randomized clinical trial comparing oncological outcomes of D2BJS open · 2019Article
- Initial experience of laparoscopic right hemicolectomy with complete mesocolic excision in Singapore: a case series.Singapore medical journal · 2019Article
- Preoperative anatomical road mapping reduces variability of operating time, estimated blood loss, and lymph node yield in right colectomy with extended D3 mesenterectomy for cancer.International journal of colorectal disease · 2019Article
- Randomized clinical trial of high versus low inferior mesenteric artery ligation during anterior resection for rectal cancer.BJS open · 2018Article
- Surgical and oncological outcomes after complete mesocolic excision in right-sided colon cancer compared with conventional surgery: a retrospective, single-institution study.International journal of colorectal disease · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
No one doubts that lymph node dissection in colon cancer is necessary, it is just the extent of that dissection that is still under debate. As the individual steps of an oncologic operation cannot be separated from each other, analysis of the significance of lymph node dissection alone is difficult. It has been proven that the T category is directly related to the number and central spread of lymph node metastases. Micrometastases and isolated tumor cells may be detected in lymph nodes by using special staining techniques; their presence may worsen prognosis significantly and approximate it to UICC stage III. The numbers of dissected lymph nodes and the ratio of involved versus dissected lymph nodes have been used as markers for quality of surgery and histopathological evaluation. Recent results underscore the importance of technique and extent of dissection. Dissection must be performed along the embryologic planes of the mesocolon and leave them intact. A high vascular tie with preservation of the central hypogastric nerves must be applied in order to achieve the best oncologic results while preserving quality of life. Extended lymphadenectomy is oncologically relevant only when it is combined with removal of the primary tumor with adequate longitudinal clearance, an intact complete mesocolon, and high vascular tie. It is part of a concept in which the tumor-bearing specimen is harvested as an enveloped package to minimize the risk of tumor cell spillage and local recurrence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.