Evidence map›Paper›PMID 23753844›Full record

ReviewCirculation2013

Postural tachycardia syndrome (POTS).

Satish R Raj

3 registry-linked trialsAbstract readCase ReportsReview
In one paragraph

Review in Circulation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 132 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03253120 nacompletednot on this mapstarted 2017, after this paper: background citation

Alterations of Attention in Patients With Postural Tachycardia Syndrome and Healthy Controls Depending on Body Position and Hydration

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2017 to 2022Enrolled30ConditionsPostural Tachycardia SyndromeArmsWater
NCT04632134 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Long-term Effects of Transcutaneous Vagal Nerve Stimulation on Symptoms and Cardiovascular Autonomic Profile of Patients With Postural Orthostatic Tachycardia Syndrome (POTS)

TypeinterventionalSponsorIstituto Clinico HumanitasRan2019 to 2022Enrolled23ConditionsOrthostatic Intolerance, Postural Tachycardia Syndrome, Syncope, Postural, Physical DisabilityArmsTranscutaneous vagal nerve stimulation (tVNS), Placebo, Home daily transcutaneous vagal nerve stimulation
NCT06672861 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Development and Validation of the Kansas City Cardiac Dysautonomia Questionnaire (KCDysQ) in Patients With Postural Orthostatic Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Other Disorders of Cardiac Dysautonomia

TypeinterventionalSponsorKansas City Heart Rhythm Research FoundationRan2026 to 2026Enrolled100ConditionsCardiac DysautonomiaArmsKansas City Cardiac Dysautonomia Questionnaire (KCDysQ)
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Efficacy of Propranolol, Bisoprolol, and Pyridostigmine for Postural Tachycardia Syndrome: a Randomized Clinical Trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018
    Trial
  5. Inspiratory resistance improves postural tachycardia: a randomized study.Circulation. Arrhythmia and electrophysiology · 2015
    Trial
  6. Trial
  7. Trial
  8. Understanding the placebo effect in clinical trials for postural tachycardia syndrome.Clinical and experimental pharmacology & physiology · 2014
    Trial
  9. Trial
  10. Review
  11. The hidden burden: connective tissue, mast cell, and autoimmune comorbidities cluster in POTS with endometriosis.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Article
  12. Diagnostic strategies, test accuracy, and misdiagnosis of POTS: a narrative review of diagnostic criteria, tests, and diagnostic delay.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Satish R RajAA3228 Medical Center N, Vanderbilt University, 1161 21st Ave S, Nashville, TN 37232-2195, USA. satish.raj@vanderbilt.edu

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Structural genomics of norepinephrine transportersP01HL056693 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ROBERTSON, DAVID HERLIE · 1997 to 2016
$30.8M
Training CoreU54NS065736 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BIAGGIONI, ITALO · 2009 to 2018
$11.6M
Aldosterone and Sodium Regulation in Postural Tachycardia SyndromeR01HL102387 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GARLAND, EMILY M · 2010 to 2014
$2.1M
NCATS NIH HHS UL1 TR000445NHLBI NIH HHS P01 HL056693NHLBI NIH HHS P01 HL56693NHLBI NIH HHS R01 HL102387NINDS NIH HHS U54 NS065736
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PostureAdultAndrostenesAnxietyBlood VolumeCardiovascular AgentsCatheter AblationCombined Modality TherapyConfusionContraindicationsDiagnosis, DifferentialFatigueFemaleHemodynamicsHumansLegAndrostenesCardiovascular AgentsdrospirenoneNorepinephrineNorepinephrine Plasma Membrane Transport ProteinsSLC6A2 protein, humanSodium Chloride

Identifiers

PMID23753844
PMCPMC3756553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.