Evidence map›Paper›PMID 23753029›Full record

ArticleHaematologica2013

In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline.

Jason H Mendler, Kati Maharry, Heiko Becker, Ann-Kathrin Eisfeld, Leigha Senter, Krzysztof Mrózek, Jessica Kohlschmidt, Klaus H Metzeler, Sebastian Schwind, Susan P Whitman and 7 more

Abstract readCase ReportsLetter
In one paragraph

Article in Haematologica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Acute myeloid leukemia with concurrentLeukemia research reports · 2023
    Article
  3. [RUNX1 gene mutations are associated with adverse prognosis of patients with acute myeloidleukemia].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Jason H Mendler
Kati Maharry
Heiko Becker
Ann-Kathrin Eisfeld
Leigha Senter
Krzysztof Mrózek
Jessica Kohlschmidt
Klaus H Metzeler
Sebastian Schwind
Susan P Whitman
Jihane Khalife
Michael A Caligiuri
Rebecca B Klisovic
Joseph O Moore
Thomas H Carter
Guido Marcucci
Clara D Bloomfield

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overCore Binding Factor Alpha 2 SubunitFemaleGerm-Line MutationHumansLeukemia, Myeloid, AcuteMaleMiddle AgedNuclear ProteinsNucleophosminCore Binding Factor Alpha 2 SubunitNPM1 protein, humanNuclear ProteinsNucleophosminRUNX1 protein, humanacute myeloid leukemiamutational interrelationshipsmutationsNPM1RUNX1

Identifiers

PMID23753029
PMCPMC3729891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.