ReviewNature reviews. Genetics2013
Genomic and epigenetic insights into the molecular bases of heterosis.
Review in Nature reviews. Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 267 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
267 citing papers in PubMed, 564 citations in OpenAlex.
- Genome-wide cyclin gene evolution in Arabidopsis and Brassica reveals polyploidization-driven duplication and flowering-time associations.Molecular genetics and genomics : MGG · 2026Article
- Diurnal dynamics of maize gene expression is associated with phyllosphere microbiome composition.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Dosage-Associated Maternal Dominance and Tissue-Specific Paternal Expression in a Triploid Hybrid Between Grass Carp and Yellowcheek.Animals : an open access journal from MDPI · 2026Article
- Genetic recombination shapes complex hybrid effects across the pig genome.National science review · 2026Article
- Variations among Nile tilapia reproductive strains: An integrative morphometric and molecular approach.Journal of fish biology · 2026Article
- Enhanced metabolic benefits of dietary methionine restriction in cold resistant hybrid UCP1-deficient mice.The Journal of nutritional biochemistry · 2026Article
- Gut microbiota and their metabolites contribute to the heterosis of breast muscle yield in broilers.Journal of animal science and biotechnology · 2026Article
- Association mapping of hybrid seed set and heterosis in a central European multi-parental wheat population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Chromatin accessibility landscape and its association with heterosis in maize hybrids.Nature communications · 2026Article
- Review
- Genome-wide reprogramming of sRNA and lncRNA in the epigenetic regulation following interspecific hybridization in the Brassica species.Molecular horticulture · 2026Article
- Ecological Memory in Plants: Epigenetic Integration of Abiotic Stress and Climate Change.Plants (Basel, Switzerland) · 2026Review
- Decoding epigenetic drived heterosis in upland cotton (Gossypium hirsutum L.) through Multi-omics integration.Functional & integrative genomics · 2026Article
- Deciphering the cellular basis of heterosis in pigs through single-cell transcriptomics of growth axis-related tissues.BMC genomics · 2026Article
- Intergeneric chromosomal transfer in yeast results in improved phenotypes and widespread transcriptional responses.Nature communications · 2026Article
- Physiological determinants of heterosis in hybrid rice (Frontiers in plant science · 2026Article
- Heterosis unveiled in root-related traits and saikosaponins content between triploid FFrontiers in plant science · 2026Article
- Preliminary study on comparative non-targeted metabolomics analysis sheds light on the chemical diversity of citrus fruit pulps.PloS one · 2026Article
- Molecular and Genetic Characterization of Newly Released CIMMYT Inbred Maize Lines.Plants (Basel, Switzerland) · 2025Article
- Quantitative Insights into the Genetic Mechanisms of Crop Heterosis.Advanced genetics (Hoboken, N.J.) · 2025Review
207 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
Abstract
Heterosis, also known as hybrid vigour, is widespread in plants and animals, but the molecular bases for this phenomenon remain elusive. Recent studies in hybrids and allopolyploids using transcriptomic, proteomic, metabolomic, epigenomic and systems biology approaches have provided new insights. Emerging genomic and epigenetic perspectives suggest that heterosis arises from allelic interactions between parental genomes, leading to altered programming of genes that promote the growth, stress tolerance and fitness of hybrids. For example, epigenetic modifications of key regulatory genes in hybrids and allopolyploids can alter complex regulatory networks of physiology and metabolism, thus modulating biomass and leading to heterosis. The conceptual advances could help to improve plant and animal productivity through the manipulation of heterosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.